As per basic Gallbladder.
Classify cholecystitis as acute, chronic or both acute and chronic.
Findings in acute cholecystisis
Main initial features are edema and hemorrhage.
- Initially often also congestion and fibrin deposition in and around the muscular layer.
- Later often necrosis of the mucosa and and deeper layers, with neutrophils.
- Variable reactive epithelial changes, which may resemble dysplasia.
There may be fresh thrombi within small veins.
Findings in chronic cholecystitis
Typical features are:
- Smooth muscle hypertrophy in the muscularis
- Mild inflammatory infiltrates
- Rokitansky-Aschoff sinuses
Other findings favoring the diagnosis are:
- Granulomas (from ruptured Rokitansky-Aschoff sinuses) strogly favor the diagnosis.
- Hyalinized collagen
- Dystrophic calcification
- Lymphoid aggregates
- Atrophic and/or ulcerated mucosa
- Metaplastic changes, such as gastric or intestinal mucosa
For a general gallbladder screening, see gallbladder.
Look for reactive lymphadenopathy or metastasis.
- Further information: Lymph node
- Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Reuter, Victor E; Stoler, Mark H (2009). Sternberg's Diagnostic Surgical Pathology (5th ed.). Lippincott Williams & Wilkins. ISBN 978-0781779425.
- Hanni Gulwani. Gallbladder & extrahepatic bile ducts - Cholecystitis. Pathology Outlines. Topic Completed: 1 September 2012. Minor changes: 5 September 2019
- Hanni Gulwani. Gallbladder - Cholecystitis - Chronic cholecystitis. Topic Completed: 1 September 2012. Revised: 9 January 2020