Generally 10% neutral buffered formalin.
- See also: General notes on fixation
On this resource, the following formatting is used for comprehensiveness:
- Minimal depth
- (Moderate depth)
- Further information: Appendix
A major visual clue to chronic appendicitis is fibrosis.
(When the referral and/or history suggests chronic appendicitis, take additional slices for microscopy.)[notes 2]
- Further information: Appendicitis
Chronic appendicitis has predominantly mononuclear infiltrate rather than neutrophilic. It must go beyond the normal histological locations of mononuclear leucocytes of the appendix.
Even when chronic appendicitis is detected, also look for acute appendicitis, as well as appendix cancer.(Further information: Appendix )
(Note even the absence of acute appendicitis.)