Irradiated blood

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Author: Mikael Häggström [notes 1]
Cellular blood components for the following patients/situations should be irradiated to reduce the risk of transfusion associated graft-versus-host disease:[1]

  • Hematopoietic stem cell (HSC) transplant recipients
  • HSC transplant candidates under some circumstances
  • HSC donors if allogeneic transfusion must be given prior to completing the harvest
  • Congenital T-cell immune deficiency
  • Intrauterine or neonatal exchange transfusion
  • Transfusion from family members or HLA-selected donors
  • Patients who have had fludarabine chemotherapy
  • Hodgkin’s disease
  • Leukemia
  • Lymphoproliferative disorders
  • Granulocyte transfusion
  • Neonates
  • Aggressive chemotherapy, radiotherapy or T-cell immunosuppression

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

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