Lipomatous tumor

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Author: Mikael Häggström [notes 1]

Lipomatous tumor.

Fixation

Generally 10% neutral buffered formalin.

See also: General notes on fixation

Gross processing

  • Perform consecutive slicing of the entire specimen.
  • Look for signs of liposarcoma: Mainly by firm volumes.[1] Color varies from yellow to white (and firm) depending on the proportion of adipocytic, fibrous and/or myxoid content.[2] Areas of fat necrosis are common in larger lesions. Rarely, infiltrative growth is seen.[2]
  • Submit slices from any suspicious parts, or at least one representative slice from the specimen.

Gross report

  • Color
  • Even absence of hemorrhage or necrosis.

Example:

Mass weighing 121 grams and measuring 10 x 6,5 x 3,5 cm. Homogenous yellow color. No hemorrhage or necrosis.
See also: General notes on gross processing

Microscopic evaluation

A pedunculated lipomatous skin tumor may be a pedunculated lipofibroma:

Microscopy/Histopathology report

For lipomas: Absence of signs of malignancy.

Histopathology of lipoma.jpg

Tissue composed of univacuolar fat cells and delicate and inconspicuous fibrous septa. No evidence of malignancy.
-Lipoma.

See also: General notes on reporting

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

References

  1. Monica Dahlgren, Janne Malina, Anna Måsbäck, Otto Ljungberg (1997-02-13). Lilla utskärningen.
  2. 2.0 2.1 Andreas F Mavrogenis, Panayiotis J Papagelopoulos (2013-02-01). Soft Tissues: Well-differentiated liposarcoma. Atlas of Genetics and Cytogenetics in Oncology and Haematology.
  3. . Lipoma Variant: Fibrolipoma. Stanford University School of Medicine. Retrieved on 2020-02-10.
  4. Michael R. Clay. Soft tissue - Adipose tissue - Myxoid liposarcoma. PathologyOutlines. Topic Completed: 1 January 2018. Revised: 20 March 2019