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Author: Mikael Häggström [notes 1]

Gross processing

  • Measure the specimen
  • Put in decalcification, after bisection of visibly affected areas if needed for penetration of the solution
  • Take sections of visibly afected areas.
  • Potentially sample as a standard amputation

Microscopic evaluation

The main sign of acute osteomyelitis is the presence of numerous neutrophils in the stroma. It may also have lymphocytes, plasma cells, bone necrosis,' capillary proliferation and fibrosis.[1]


  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page


  1. Dariusz Borys. Bone & joints - Osteomyelitis - Bacterial osteomyelitis (acute). PathologyOutlines. Topic Completed: 1 June 2012. Minor changes: 28 June 2019