Difference between revisions of "Appendicitis"
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[[File:Acute suppurative appendicitis with perforation.jpg|thumb|Acute suppurative appendicitis with transmural inflammation, with associated perforation (at right).]] | [[File:Acute suppurative appendicitis with perforation.jpg|thumb|Acute suppurative appendicitis with transmural inflammation, with associated perforation (at right).]] | ||
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− | |+ Classification of acute appendicitis based on | + | |+ Classification of acute appendicitis based on gross pathology and light microscopy characteristics<ref name="Carr2000">Unless otherwise specified in rows, reference is:<br>- {{cite journal|last1=Carr|first1=Norman J.|title=The pathology of acute appendicitis|journal=Annals of Diagnostic Pathology|volume=4|issue=1|year=2000|pages=46–58|issn=10929134|doi=10.1016/S1092-9134(00)90011-X}}</ref> |
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! Pattern !! Gross pathology !! Light microscopy !! Clinical significance | ! Pattern !! Gross pathology !! Light microscopy !! Clinical significance |
Revision as of 09:41, 1 September 2020
Author:
Mikael Häggström [note 1]
Appendicitis may histopathologically be defined as neutrophilic infiltrates of the wall of the appendix in the correct clinical context.
See also: General notes on fixation
Contents
Comprehensiveness
Comprehensiveness
On this resource, the following formatting is used for comprehensiveness:
- Minimal depth
- (Moderate depth)
- ((Comprehensive))
Gross proccessing
Standard sections if the appendix appears inflamed and there are no signs of malignancy. Further information: Appendix
Microscopic evaluation
- Evaluate depth of the inflammation.
- Look for any perforation of the wall.
- Look for cancerous cells (which may have caused the appendicitis). Further information: Appendix
- (Attempt to specify the type of appendicitis as either of the following:)
Types
Pattern | Gross pathology | Light microscopy | Clinical significance |
---|---|---|---|
Acute intraluminal inflammation | None visible |
|
Probably none |
Acute mucosal inflammation | None visible |
|
May be secondary to enteritis. |
Suppurative acute appendicitis | May be inapparent.
|
|
Can be presumed to be primary cause of symptoms |
Gangrenous/necrotizing appendicitis |
|
|
Will perforate if untreated |
Periappendicitis | May be inapparent.
|
|
If isolated, probably secondary to other disease |
Eosinophilic appendicitis | None visible |
|
Possibly parasitic, or eosinophilic enteritis. |
Chronic appendicitis[2] |
|
|
Should preferably correlate with long-term or recurrent symptoms. |
Microscopy report
Should include, if detected:
- Acute or chronic appendicitis
- Depth of inflammation
- Any abscess and\or perforation
- Necrosis and\or ulceration, at least if transmural
(Classification into one or several types as per table above.)
- Example
Acute appendicitis and periappendicitis with transmural necrosis
Notes
Main pageReferences
Image sources
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