Difference between revisions of "Cholecystitis"
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m (Mikael Häggström moved page Chronic cholecystitis to Cholecystitis: Generalized) |
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− | + | Inflammation of the '''[[gallbladder]]''': | |
+ | |||
+ | ==Gross processing== | ||
+ | As per basic '''[[Gallbladder]]'''. | ||
==Microscopic evaluation== | ==Microscopic evaluation== | ||
+ | ===Findings in '''acute''' cholecystisis=== | ||
+ | *Initially edema, congestion, hemorrhage, fibrin deposition in and around muscular layer | ||
+ | *Later mucosal and mural necrosis with neutrophils | ||
+ | *Variable reactive epithelial changes resembling dysplasia | ||
+ | *Finally myofibroblastic proliferation with chronic inflammatory infiltrate | ||
+ | *Also fresh thrombi within small veins | ||
+ | |||
+ | ===Findings in '''chronic''' cholecystitis=== | ||
[[File:Gallbladder- Rokitansky-Aschoff Sinus (15144904071).jpg|thumb|Rokitansky-Aschoff sinus.]] | [[File:Gallbladder- Rokitansky-Aschoff Sinus (15144904071).jpg|thumb|Rokitansky-Aschoff sinus.]] | ||
Typical features are:<ref name=Gulwani2020>{{cite web|url=https://www.pathologyoutlines.com/topic/gallbladderchroniccholecystitis.html|title=Gallbladder - Cholecystitis - Chronic cholecystitis|author=Hanni Gulwani}} Topic Completed: 1 September 2012. Revised: 9 January 2020</ref> | Typical features are:<ref name=Gulwani2020>{{cite web|url=https://www.pathologyoutlines.com/topic/gallbladderchroniccholecystitis.html|title=Gallbladder - Cholecystitis - Chronic cholecystitis|author=Hanni Gulwani}} Topic Completed: 1 September 2012. Revised: 9 January 2020</ref> |
Revision as of 15:48, 13 August 2020
Author:
Mikael Häggström [note 1]
Inflammation of the gallbladder:
Contents
Gross processing
As per basic Gallbladder.
Microscopic evaluation
Findings in acute cholecystisis
- Initially edema, congestion, hemorrhage, fibrin deposition in and around muscular layer
- Later mucosal and mural necrosis with neutrophils
- Variable reactive epithelial changes resembling dysplasia
- Finally myofibroblastic proliferation with chronic inflammatory infiltrate
- Also fresh thrombi within small veins
Findings in chronic cholecystitis
Typical features are:[1]
- Smooth muscle hypertrophy in the muscularis
- Mild inflammatory infiltrates
- Rokitansky-Aschoff sinuses
Other findings favoring the diagnosis are:[1]
- Granulomas (from ruptured Rokitansky-Aschoff sinuses) strogly favor the diagnosis.
- Hyalinized collagen
- Dystrophic calcification
- Lymphoid aggregates
- Atrophic and/or ulcerated mucosa
- Metaplastic changes, such as gastric or intestinal mucosa
For a general gallbladder screening, see gallbladder.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Hanni Gulwani. Gallbladder - Cholecystitis - Chronic cholecystitis. Topic Completed: 1 September 2012. Revised: 9 January 2020
Image sources