Difference between revisions of "Cholecystitis"
Jump to navigation
Jump to search
(→Findings in acute cholecystisis: Bolded) |
m (→Findings in acute cholecystisis: Format) |
||
Line 10: | Line 10: | ||
==Microscopic evaluation== | ==Microscopic evaluation== | ||
===Findings in '''acute''' cholecystisis=== | ===Findings in '''acute''' cholecystisis=== | ||
− | Main initial features are '''edema''' and '''hemorrhage'''.<ref name=Mills>{{cite book |author= Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Reuter, Victor E; Stoler, Mark H | + | Main initial features are '''edema''' and '''hemorrhage'''.<ref name=Mills>{{cite book |author= Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Reuter, Victor E; Stoler, Mark H |title=Sternberg's Diagnostic Surgical Pathology |publisher=Lippincott Williams & Wilkins |location= |year=2009 |pages=|edition=5th |isbn=978-0781779425 |oclc= |doi= |accessdate=}}<\ref> |
*Initially often also congestion and fibrin deposition in and around the muscular layer.<ref name=Gulwani-acute>{{cite web|url=https://www.pathologyoutlines.com/topic/gallbladderacutecholecystitis.html|title=Gallbladder & extrahepatic bile ducts - Cholecystitis|author=Hanni Gulwani|website=Pathology Outlines}} Topic Completed: 1 September 2012. Minor changes: 5 September 2019</ref> | *Initially often also congestion and fibrin deposition in and around the muscular layer.<ref name=Gulwani-acute>{{cite web|url=https://www.pathologyoutlines.com/topic/gallbladderacutecholecystitis.html|title=Gallbladder & extrahepatic bile ducts - Cholecystitis|author=Hanni Gulwani|website=Pathology Outlines}} Topic Completed: 1 September 2012. Minor changes: 5 September 2019</ref> | ||
*Later often '''necrosis''' of the mucosa and and deeper layers, with neutrophils.<ref name=Gulwani-acute/> | *Later often '''necrosis''' of the mucosa and and deeper layers, with neutrophils.<ref name=Gulwani-acute/> |
Revision as of 16:16, 13 August 2020
Author:
Mikael Häggström [note 1]
Inflammation of the gallbladder:
Contents
Gross processing
As per basic Gallbladder.
Microscopic evaluation
Findings in acute cholecystisis
Main initial features are edema and hemorrhage.Cite error: Closing </ref>
missing for <ref>
tag
- Later often necrosis of the mucosa and and deeper layers, with neutrophils.[1]
- Variable reactive epithelial changes, which may resemble dysplasia.[1]
There may be fresh thrombi within small veins.[1]
Findings in chronic cholecystitis
Typical features are:[2]
- Smooth muscle hypertrophy in the muscularis
- Mild inflammatory infiltrates
- Rokitansky-Aschoff sinuses
Other findings favoring the diagnosis are:[2]
- Granulomas (from ruptured Rokitansky-Aschoff sinuses) strogly favor the diagnosis.
- Hyalinized collagen
- Dystrophic calcification
- Lymphoid aggregates
- Atrophic and/or ulcerated mucosa
- Metaplastic changes, such as gastric or intestinal mucosa
For a general gallbladder screening, see gallbladder.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
Image sources