Difference between revisions of "Esophagus"

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|author1=[[User:Mikael Häggström|Mikael Häggström]]
 
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Most common requests:
 
Most common requests:
 
:*[[Eosinophilic esophagitis]]
 
:*[[Eosinophilic esophagitis]]
 
 
Subregions:
 
Subregions:
 
*[[Gastroesophageal junction]], preferably also evaluate as such for lower esophagus, or where esophagus level is not specified.
 
*[[Gastroesophageal junction]], preferably also evaluate as such for lower esophagus, or where esophagus level is not specified.
  
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This article deals with esophageal biopsies. For resections, see: '''[[Esophagus resection]]'''
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{{Comprehensiveness}}</noinclude>
 
==Microscopic evaluation==
 
==Microscopic evaluation==
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On esophageal biopsies, look at least for esophagitis:
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{{Esophagitis}}
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===Microscopy report===
 
Example normal report for an esophagus biopsy:
 
Example normal report for an esophagus biopsy:
 
{|class=wikitable
 
{|class=wikitable
| (Middle third esophagus, biopsy:)<br>Squamous mucosa without significant histopathologic changes.<br>Negative for [[eosinophilic esophagitis]].
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| {{Moderate-begin}}Middle third esophagus, biopsy:{{Moderate-end}}<br>Squamous mucosa without significant histopathologic changes.<br>{{Comprehensive-begin}}Negative for [[eosinophilic esophagitis]].{{Comprehensive-end}}
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Example report with signs of reflux:
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| {{Moderate-begin}}Mid esophagus, biopsy:{{Moderate-end}}<br>Squamous mucosa with reactive changes consistent with reflux.<br>{{Comprehensive-begin}}Negative for [[eosinophilic esophagitis]].{{Comprehensive-end}}
 
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Latest revision as of 19:23, 2 December 2022

Author: Mikael Häggström [note 1]

Endoscopic biopsies   edit
Mostly:

Most common requests:

Subregions:

This article deals with esophageal biopsies. For resections, see: Esophagus resection

Comprehensiveness

On this resource, the following formatting is used for comprehensiveness:

  • Minimal depth
  • (Moderate depth)
  • ((Comprehensive))

Microscopic evaluation

On esophageal biopsies, look at least for esophagitis:

Esophagitis

GE junction with chronic esophagitis, including plasma cells (black arrow), an acute inflammation with neutrophils (white arrow), as well as basal layer hyperplasia (yellow double-headed arrow).

Look for signs of (reflux) esophagitis, mainly:[1]

  • Inflammatory cells, especially when intra-epithelial. Neutrophils confer a diagnosis of acute inflammation, while plasma cells, eosinophils and excess T cells confer a diagnosis of chronic inflammation. In eosinophil-predominant inflammation, also evaluate as suspected eosinophilic esophagitis.
  • Basal cell hyperplasia exceeding 15 - 20% of the epithelial thickness.
  • Stromal papillae reaching upper third of the epithelium.
  • Loss of orientation of superficial epithelial cells.
  • Ballooned squamous cells

Microscopy report

Example normal report for an esophagus biopsy:

(Middle third esophagus, biopsy:)
Squamous mucosa without significant histopathologic changes.
((Negative for eosinophilic esophagitis.))

Example report with signs of reflux:

(Mid esophagus, biopsy:)
Squamous mucosa with reactive changes consistent with reflux.
((Negative for eosinophilic esophagitis.))

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Elliot Weisenberg. Esophagus - Esophagitis - Reflux esophagitis / gastroesophageal reflux disease. Pathology Outlines. Topic Completed: 1 October 2012. Minor changes: 8 July 2020

Image sources