Difference between revisions of "Gallbladder"
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| + | ==Common requests== | ||
| + | *'''[[Chronic cholecystitis]]''' | ||
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==Basic autopsy cutting== | ==Basic autopsy cutting== | ||
[[File:Gross pathology of gallbladder carcinoma.jpg|thumb|Gross pathology of gallbladder carcinoma, with a prominent nodule.]] | [[File:Gross pathology of gallbladder carcinoma.jpg|thumb|Gross pathology of gallbladder carcinoma, with a prominent nodule.]] | ||
May be done by a distal-to-proximal approach: Identify the ''ampulla of Vater'', possibly by bile flow when squeezing the gallbladder. Dissect the common bile duct, cystic duct and thereafter the gallbladder. Look mainly for signs of carcinoma. | May be done by a distal-to-proximal approach: Identify the ''ampulla of Vater'', possibly by bile flow when squeezing the gallbladder. Dissect the common bile duct, cystic duct and thereafter the gallbladder. Look mainly for signs of carcinoma. | ||
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<gallery> | <gallery> | ||
File:Gross pathology of cholesterolosis.jpg|thumb|Cholesterolosis (yellow streaks of cholesterol deposition) is a frequent incidental finding.<ref>{{cite journal|last1=Talwar|first1=OP|last2=K.C.|first2=Geetika|title=Histomorphological changes in gall bladder diseases and its association with helicobacter infection|journal=Journal of Pathology of Nepal|volume=4|issue=8|year=2014|pages=617–622|issn=2091-0908|doi=10.3126/jpn.v4i8.11607}}<br>- "Figures - available via license: CC BY 4.0"</ref> | File:Gross pathology of cholesterolosis.jpg|thumb|Cholesterolosis (yellow streaks of cholesterol deposition) is a frequent incidental finding.<ref>{{cite journal|last1=Talwar|first1=OP|last2=K.C.|first2=Geetika|title=Histomorphological changes in gall bladder diseases and its association with helicobacter infection|journal=Journal of Pathology of Nepal|volume=4|issue=8|year=2014|pages=617–622|issn=2091-0908|doi=10.3126/jpn.v4i8.11607}}<br>- "Figures - available via license: CC BY 4.0"</ref> | ||
</gallery> | </gallery> | ||
| + | {{Further|Autopsy}} | ||
| + | {{Fixation - standard}} | ||
| + | {{Fixation - general notes}} | ||
==Microscopic evaluation== | ==Microscopic evaluation== | ||
| − | <gallery> | + | Look at least at the epithelial lining, for atypia. |
| − | File:Histopathology of gallbladder carcinoma.jpg|Histopathology of gallbladder carcinoma, with marked nuclear pleomorphism | + | <gallery mode=packed heights=200> |
| − | File:Histopathology of | + | File:Histopathology of gallbladder carcinoma.jpg|Histopathology of gallbladder '''carcinoma''', with marked nuclear pleomorphism |
| + | </gallery> | ||
| + | |||
| + | ===Common findings=== | ||
| + | Report if incidentally discovered: | ||
| + | <gallery mode=packed heights=200> | ||
| + | File:Histopathology of cholesterolosis, with annotated foam cell.jpg|Substantial amount of '''foam cells''' within lamina propria, conferring a diagnosis of cholesterolosis. | ||
</gallery> | </gallery> | ||
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==Report== | ==Report== | ||
{{Comprehensiveness}} | {{Comprehensiveness}} | ||
{{Gallbladder report}} | {{Gallbladder report}} | ||
{{Bottom}} | {{Bottom}} | ||
Revision as of 11:17, 19 March 2020
Author:
Mikael Häggström [note 1]
Contents
Common requests
Basic autopsy cutting
May be done by a distal-to-proximal approach: Identify the ampulla of Vater, possibly by bile flow when squeezing the gallbladder. Dissect the common bile duct, cystic duct and thereafter the gallbladder. Look mainly for signs of carcinoma.
Cholesterolosis (yellow streaks of cholesterol deposition) is a frequent incidental finding.[1]
Further information: Autopsy
Fixation
Generally 10% neutral buffered formalin.
See also: General notes on fixation
Microscopic evaluation
Look at least at the epithelial lining, for atypia.
Histopathology of gallbladder carcinoma, with marked nuclear pleomorphism
Common findings
Report if incidentally discovered:
Substantial amount of foam cells within lamina propria, conferring a diagnosis of cholesterolosis.
Report
Comprehensiveness
On this resource, the following formatting is used for comprehensiveness:
- Minimal depth
- (Moderate depth)
- ((Comprehensive))
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
Image sources
