Difference between revisions of "Gastritis"
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Inflammation of the [[stomach]]: | Inflammation of the [[stomach]]: | ||
==Microscopy evaluation== | ==Microscopy evaluation== | ||
− | [[File:Histopathology of mild active gastritis, annotated.jpg|thumb|Histopathology of mild active gastritis, with intraepithelial neutrophils (white arrows) as well as in lamina propria (black arrows).]] | + | [[File:Histopathology of mild active gastritis, annotated.jpg|thumb|Histopathology of '''mild active gastritis''', with intraepithelial neutrophils (white arrows) as well as in lamina propria (black arrows).]] |
*'''Mild acute gastritis:'''<ref name=PathologyOutlinesAcute>{{cite web|url=https://www.pathologyoutlines.com/topic/stomachacutegastritis.html|title=Stomach - Gastritis - Acute gastritis|author=Elliot Weisenberg|website=pathologyOutlines}} Topic Completed: 1 August 2012. Minor changes: 31 August 2020</ref> | *'''Mild acute gastritis:'''<ref name=PathologyOutlinesAcute>{{cite web|url=https://www.pathologyoutlines.com/topic/stomachacutegastritis.html|title=Stomach - Gastritis - Acute gastritis|author=Elliot Weisenberg|website=pathologyOutlines}} Topic Completed: 1 August 2012. Minor changes: 31 August 2020</ref> | ||
:*Modest '''edema''' of lamina propria | :*Modest '''edema''' of lamina propria | ||
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:*Nearby epithelium may show '''regenerative''' changes | :*Nearby epithelium may show '''regenerative''' changes | ||
*'''Chronic gastritis'''<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/stomachchronicgastritis.html|title=Stomach - Gastritis - Chronic gastritis|author=Elliot Weisenberg|website=PathologyOutlines}} Topic Completed: 1 August 2012. Minor changes: 31 August 2020</ref> | *'''Chronic gastritis'''<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/stomachchronicgastritis.html|title=Stomach - Gastritis - Chronic gastritis|author=Elliot Weisenberg|website=PathologyOutlines}} Topic Completed: 1 August 2012. Minor changes: 31 August 2020</ref> | ||
− | [[File:Histopathology of mucosal plasma cell infiltrate in chronic gastritis.jpg|thumb|Mucosal plasma cell infiltrate in mild chronic gastritis.]] | + | [[File:Histopathology of mucosal plasma cell infiltrate in chronic gastritis.jpg|thumb|Mucosal plasma cell infiltrate in '''mild chronic gastritis'''.]] |
:*Presence of '''plasma cells''', '''lymphocytes''', and occasionally lymphoid '''follicles'''. Eosinophils and neutrophils may be present. | :*Presence of '''plasma cells''', '''lymphocytes''', and occasionally lymphoid '''follicles'''. Eosinophils and neutrophils may be present. | ||
:*'''Reduced mucin''' in the cytoplasm | :*'''Reduced mucin''' in the cytoplasm |
Revision as of 15:53, 1 December 2020
Author:
Mikael Häggström [note 1]
Inflammation of the stomach:
Contents
Microscopy evaluation
- Mild acute gastritis:[1]
- Modest edema of lamina propria
- Vascular congestion
- Scattered neutrophils
- Mucosal hemorrhage
- Intact epithelium
- Moderate to severe acute gastritis:[1]
- Loss of superficial epithelium above the muscularis mucosa
- Hemorrhage
- Variable infiltrate with neutrophils
- Fibrinopurulent luminal exudate
- Nearby epithelium may show regenerative changes
- Chronic gastritis[2]
- Presence of plasma cells, lymphocytes, and occasionally lymphoid follicles. Eosinophils and neutrophils may be present.
- Reduced mucin in the cytoplasm
- Enlargement of nuclei and nucleoi
- Subnuclear vacuolation in antral glands or pits (which is PAS negative)
- Intestinal metaplasia: with partial replacement of the mucosa of the antrum and body with metaplastic goblet cells of intestinal morphology, absorptive cells and Paneth cells.
When gastritis is present, also evaluate as a stomach biopsy for Helicobacter pylori.
Microscopy report
Chronic gastritis without neutrophils is preferably also termed "non-active".
Example:
(Gastric, biopsy:) Mild chronic non-active gastritis, non-specific. Negative for Helicobacter pylori organisms on H&E slide. |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Elliot Weisenberg. Stomach - Gastritis - Acute gastritis. pathologyOutlines. Topic Completed: 1 August 2012. Minor changes: 31 August 2020
- ↑ Elliot Weisenberg. Stomach - Gastritis - Chronic gastritis. PathologyOutlines. Topic Completed: 1 August 2012. Minor changes: 31 August 2020
Image sources