Gastritis
Revision as of 15:53, 1 December 2020 by Mikael Häggström (talk | contribs) (→Microscopy evaluation: Bolded)
Author:
Mikael Häggström [note 1]
Inflammation of the stomach:
Contents
Microscopy evaluation
- Mild acute gastritis:[1]
- Modest edema of lamina propria
- Vascular congestion
- Scattered neutrophils
- Mucosal hemorrhage
- Intact epithelium
- Moderate to severe acute gastritis:[1]
- Loss of superficial epithelium above the muscularis mucosa
- Hemorrhage
- Variable infiltrate with neutrophils
- Fibrinopurulent luminal exudate
- Nearby epithelium may show regenerative changes
- Chronic gastritis[2]
- Presence of plasma cells, lymphocytes, and occasionally lymphoid follicles. Eosinophils and neutrophils may be present.
- Reduced mucin in the cytoplasm
- Enlargement of nuclei and nucleoi
- Subnuclear vacuolation in antral glands or pits (which is PAS negative)
- Intestinal metaplasia: with partial replacement of the mucosa of the antrum and body with metaplastic goblet cells of intestinal morphology, absorptive cells and Paneth cells.
When gastritis is present, also evaluate as a stomach biopsy for Helicobacter pylori.
Microscopy report
Chronic gastritis without neutrophils is preferably also termed "non-active".
Example:
(Gastric, biopsy:) Mild chronic non-active gastritis, non-specific. Negative for Helicobacter pylori organisms on H&E slide. |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Elliot Weisenberg. Stomach - Gastritis - Acute gastritis. pathologyOutlines. Topic Completed: 1 August 2012. Minor changes: 31 August 2020
- ↑ Elliot Weisenberg. Stomach - Gastritis - Chronic gastritis. PathologyOutlines. Topic Completed: 1 August 2012. Minor changes: 31 August 2020
Image sources