Difference between revisions of "Nasal cavity and paranasal sinuses"
Jump to navigation
Jump to search
m (Specified) |
(Expanded) |
||
(16 intermediate revisions by the same user not shown) | |||
Line 3: | Line 3: | ||
|author2= | |author2= | ||
}} | }} | ||
− | + | {{Comprehensiveness}} | |
− | ==Nasal polyps== | + | ==Nasal or sinonasal polyps== |
Look for signs of malignancy. | Look for signs of malignancy. | ||
{{Further|Evaluation of suspected malignancies}} | {{Further|Evaluation of suspected malignancies}} | ||
− | [[File:Histopathology of a nasal polyp.jpg|thumb|'''Benign nasal polyp''' (not otherwise specified), consisting of hyperplastic edematous connective tissue with some seromucous glands and | + | [[File:Histopathology of a nasal polyp.jpg|thumb|'''Benign nasal/sinonasal polyp''' (not otherwise specified), consisting of hyperplastic edematous connective tissue with some seromucous glands and inflammation (mostly neutrophils and eosinophils), surrounded by respiratory or squamous epithelium.<ref>{{Cite book|url=https://books.google.com/books?id=Zm3jBwAAQBAJ&pg=PA168|title=Ear, Nose and Throat Histopathology|last=Michaels|first=Leslie|date=2012-12-06|publisher=Springer Science & Business Media|isbn=9781447133322|language=en|page=168}}</ref> It can be termed '''inflammatory nasal/sinonasal polyp''' when inflammation is more pronounced.]] |
Main differential diagnoses: | Main differential diagnoses: | ||
− | <gallery mode=packed heights= | + | <gallery mode=packed heights=210> |
File:Histopathology of inverted papilloma.jpg|'''Inverted papilloma''', wherein the surface epithelial cells grow downward into the underlying supportive tissue. | File:Histopathology of inverted papilloma.jpg|'''Inverted papilloma''', wherein the surface epithelial cells grow downward into the underlying supportive tissue. | ||
− | File:Histopathology of nasal squamous papilloma.jpg|'''Squamous papilloma'''. | + | File:Histopathology of nasal squamous papilloma.jpg|'''Squamous papilloma''', with acanthosis and hyperkerratosis. |
</gallery> | </gallery> | ||
+ | In case of significant '''inflammation''': | ||
+ | *Take at least one high magnification look to confirm that it is mixed and that lymphocytes are not atypical (otherwise, consult hematopathology, particularly whether it could be a lymphoma, notably extranodal NK/T cell lymphoma, nasal type. | ||
+ | *{{Moderate-begin}}Classify as '''acute''' (with neutrophils) versus '''chronic''' (lymphocytes, eosinophils and/or plasma cells). Also look at any bone fragments for osteomyelitis.{{Moderate-end}} {{further|Osteomyelitis}} | ||
+ | <gallery mode=packed heights=210> | ||
+ | File:Histopathology of sinonasal inflammatory polyp with mixed inflammation, annotated.jpg|'''Benign chronic mixed inflammation''' of an inflammatory sinonasal polyp. | ||
+ | File:Histopathology of extranodal NK-T cell lymphoma, nasal type.png|'''Extranodal NK/T cell lymphoma, nasal type'''.<ref>{{cite journal| author=Takahara M, Kumai T, Kishibe K, Nagato T, Harabuchi Y| title=Extranodal NK/T-Cell Lymphoma, Nasal Type: Genetic, Biologic, and Clinical Aspects with a Central Focus on Epstein-Barr Virus Relation. | journal=Microorganisms | year= 2021 | volume= 9 | issue= 7 | pages= | pmid=34202088 | doi=10.3390/microorganisms9071381 | pmc=8304202 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=34202088 }}<br>- "This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."</ref> These lymphoma cells are typically monotonous, with folded nuclei, indistinct nucleoli and moderate amount of cytoplasm.<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/lymphomanonBnasal.html|title=Extranodal NK / T cell lymphoma, nasal type|author=Mario L. Marques-Piubelli, M.D., Carlos A. Torres-Cabala, M.D., Roberto N. Miranda, M.D.|website=Pathology Outlines}} Last author update: 5 January 2021. Last staff update: 14 October 2021</ref> | ||
+ | </gallery> | ||
+ | |||
+ | ==Reporting== | ||
+ | Example: | ||
+ | {|class=wikitable | ||
+ | | [[File:Histopathology of nasal contents with chronic inflammation.jpg|210px|left]] Right and left sinus contents, excisions:<br>Benign respiratory mucosa with chronic inflammation.<br>Bone without significant histopathologic changes. | ||
+ | |} | ||
{{Bottom}} | {{Bottom}} |
Latest revision as of 16:23, 9 October 2023
Author:
Mikael Häggström [note 1]
Contents
Comprehensiveness
On this resource, the following formatting is used for comprehensiveness:
- Minimal depth
- (Moderate depth)
- ((Comprehensive))
Nasal or sinonasal polyps
Look for signs of malignancy. Further information: Evaluation of suspected malignancies
Main differential diagnoses:
In case of significant inflammation:
- Take at least one high magnification look to confirm that it is mixed and that lymphocytes are not atypical (otherwise, consult hematopathology, particularly whether it could be a lymphoma, notably extranodal NK/T cell lymphoma, nasal type.
- (Classify as acute (with neutrophils) versus chronic (lymphocytes, eosinophils and/or plasma cells). Also look at any bone fragments for osteomyelitis.) Further information: Osteomyelitis
Reporting
Example:
Right and left sinus contents, excisions: Benign respiratory mucosa with chronic inflammation. Bone without significant histopathologic changes. |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Michaels, Leslie (2012-12-06) (in en). Ear, Nose and Throat Histopathology . Springer Science & Business Media. p. 168. ISBN 9781447133322.
- ↑ Takahara M, Kumai T, Kishibe K, Nagato T, Harabuchi Y (2021). "Extranodal NK/T-Cell Lymphoma, Nasal Type: Genetic, Biologic, and Clinical Aspects with a Central Focus on Epstein-Barr Virus Relation.
". Microorganisms 9 (7). doi: . PMID 34202088. PMC: 8304202. Archived from the original. .
- "This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)." - ↑ Mario L. Marques-Piubelli, M.D., Carlos A. Torres-Cabala, M.D., Roberto N. Miranda, M.D.. Extranodal NK / T cell lymphoma, nasal type. Pathology Outlines. Last author update: 5 January 2021. Last staff update: 14 October 2021
Image sources