Pigmented macrophages of the lung
Author:
Mikael Häggström [note 1]
When seeing pigmented macrophages of the lung, categorize as follows:
Disease | Macrophages | Pigment appearance (HE stain) | Associated medical history | Image | Image comment |
---|---|---|---|---|---|
Anthracosis | Black-brown granules | Black arrow shows interstitial anthracotic pigment. Nearby macrophages (white arrow) can be presumed to contain anthracotic pigment. Reporting is optional in mild cases in the elderly. | |||
Respiratory bronchiolitis | "Smoker's macrophages" | Yellow to light brown and finely granular[3] | Tobacco smoking | Smoker's macrophages (arrow); mild interstitial lymphocytic infiltrate and mild fibrosis (arrowhead)[4] | |
Chronic pulmonary congestion | Siderophages | Brown-golden and refractile.[5] |
|
Siderophage (black arrow), and interstitium with edema, hemosiderin deposition (black arrow) and collagenous thickening. |
Contents
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
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References
- ↑ Cotran; Kumar, Collins (1999). Robbins Pathologic Basis of Disease . Philadelphia: W.B Saunders Company. ISBN 978-0-7216-7335-6.
- ↑ Morgan WK (November 1978). "Industrial bronchitis ". Br J Ind Med 35 (4): 285–91. PMID 367424.
- ↑ William Perry, M.D., M.P.H., Kristine Konopka, M.D.. Lung - Other interstitial pneumonitis / fibrosis - Respiratory bronchiolitis. Topic Completed: 1 July 2020. Minor changes: 1 July 2020.
- ↑ Sousa, Célia; Rodrigues, Márcio; Carvalho, André; Viamonte, Bárbara; Cunha, Rui; Guimarães, Susana; de Moura, Conceição Souto; Morais, António; et al. (2019). "Diffuse smoking-related lung diseases: insights from a radiologic-pathologic correlation
". Insights into Imaging 10 (1). doi: . ISSN 1869-4101.
- This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/) - ↑ Zander, Dani (2018). Pulmonary pathology . Philadelphia, PA: Elsevier. ISBN 978-0-323-39308-9. OCLC 968711140. - VII Acute Lung Injury with Siderophages
Image sources