Difference between revisions of "Stomach biopsy for Helicobacter pylori"

From patholines.org
Jump to navigation Jump to search
m (Mikael Häggström moved page Stomach for helicobacter pylori to Stomach for ''Helicobacter pylori'': Formatting)
(Linked)
(6 intermediate revisions by the same user not shown)
Line 5: Line 5:
  
 
==Microscopic evaluation==
 
==Microscopic evaluation==
[[File:Helicobacter pylori, Gastric Mucosa, H&E (390307642).jpg|thumb|Dozens of the curved bacteria fill the lumen of a gastric foveola on H&E stain.]]
+
[[File:Helicobacter pylori, Gastric Mucosa, H&E (390307642).jpg|thumb|Helicobacter pylori on HE stain, being curved bacteria in the lumen of a gastric foveola.]]
 
Look for:
 
Look for:
*Look for ''Helicobacter pylori''-like bacteria in the lumen.
+
*''Helicobacter pylori''-like '''bacteria''' in the lumen, as curved, spirochete-like bacteria, generally in the superficial mucus layer and along microvilli of epithelial cells.<ref name=PathologyOutlines/>
*Look for associated inflammation, typically a chronic inflammatory infiltrate with germinal centers (follicular gastritis), and plasma cells in lamina propria.<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/stomachhelicobacter.html|title=Stomach - Infections - Helicobacter pylori|author=Elliot Weisenberg|website=Pathology Outlines}} Topic Completed: 1 August 2012. Minor changes: 1 September 2020</ref>
+
*Associated '''inflammation''', typically a chronic form of '''[[gastritis]]''' with germinal centers (follicular gastritis), and plasma cells in lamina propria.<ref name=PathologyOutlines>{{cite web|url=https://www.pathologyoutlines.com/topic/stomachhelicobacter.html|title=Stomach - Infections - Helicobacter pylori|author=Elliot Weisenberg|website=Pathology Outlines}} Topic Completed: 1 August 2012. Minor changes: 1 September 2020</ref><ref group=notes>Plasma cells and lymphocytes are normally found in the lamina propria of the small and large intestine, but is abnormal in the stomach.</ref> There should be at least 3 plasma cells facing each other to make a diagnosis of chronic gastritis.
  
 
===Example report===
 
===Example report===
 +
Chronic gastritis without ''H. pylori''-like organisms should be described as non-specific:
 
{|class=wikitable
 
{|class=wikitable
| Negative/Positive for ''H. pylori''-like organisms on H&E stain.
+
| Mild chronic gastritis, which is non-specific.<br>
 +
Negative for ''H. pylori''-like organisms on H&E stain.
 
|}
 
|}
 
{{Bottom}}
 
{{Bottom}}

Revision as of 17:52, 28 September 2020

Author: Mikael Häggström [note 1]

Microscopic evaluation

Helicobacter pylori on HE stain, being curved bacteria in the lumen of a gastric foveola.

Look for:

  • Helicobacter pylori-like bacteria in the lumen, as curved, spirochete-like bacteria, generally in the superficial mucus layer and along microvilli of epithelial cells.[1]
  • Associated inflammation, typically a chronic form of gastritis with germinal centers (follicular gastritis), and plasma cells in lamina propria.[1][notes 1] There should be at least 3 plasma cells facing each other to make a diagnosis of chronic gastritis.

Example report

Chronic gastritis without H. pylori-like organisms should be described as non-specific:

Mild chronic gastritis, which is non-specific.

Negative for H. pylori-like organisms on H&E stain.

Notes

  1. Plasma cells and lymphocytes are normally found in the lamina propria of the small and large intestine, but is abnormal in the stomach.
  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. 1.0 1.1 Elliot Weisenberg. Stomach - Infections - Helicobacter pylori. Pathology Outlines. Topic Completed: 1 August 2012. Minor changes: 1 September 2020

Image sources