Difference between revisions of "Thyroid"
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{{Fixation - general notes}} | {{Fixation - general notes}} | ||
==Gross processing== | ==Gross processing== | ||
− | === | + | *'''Weigh'''<ref name=chicago/> |
− | {{ | + | *'''Measure''' each lobe and isthmus in 3 dimensions, respectively.<ref name=chicago/> |
+ | *'''Ink''' outer surface,<ref name=chicago/> at least if malignancy is suspected.<ref>{{Stora utskärningen}}</ref>:{{Ink note}} | ||
+ | <gallery> | ||
+ | File:Grossing of hemithyroidectomy.svg|Hemithyroidecomy (lobe + isthmus) or lobectomy, including completion thyroidectomies: Use separate colors over the cut surface and the outer “capsular” surface.<ref group="notes" name="coloring">Separate coloring allows to distinguish the thyroid margin (continuous with the other lobe) from the peripheral margin (towards soft tissues).</ref> | ||
+ | File:How to not gross hemithyroidectomy.svg|None of the outer “capsular” surface should be inked like the cut surface.<ref group="notes" name="coloring"/> | ||
+ | File:Grossing of thyroidectomy with isthmus.svg|Intact total thyroidectomy: Separate colors for each lobe and the isthmus. | ||
+ | File:Grossing of thyroidectomy without isthmus.svg|If no appreciable isthmus, Separate colors for each lobe. | ||
+ | </gallery> | ||
+ | Serially '''section''' the specimen at 3-4mm intervals,<ref>{{cite web|url=https://www.rcpa.edu.au/Manuals/Macroscopic-Cut-Up-Manual/Endocrine/Thyroid|title=THYROID|website=Royal College of pathologists of Australia|accessdate=2019-12-17}}</ref> such as follows:<ref name=chicago/> | ||
+ | <gallery> | ||
+ | File:Sectioning of hemithyroidectomy.svg|Hemithyroidecomy (lobe + isthmus) or lobectomy: Include isthmic orange margins in your transverse sections. | ||
+ | File:Sectioning of thyroidectomy with isthmus.svg|Intact total thyroidectomy: Transverse lobe sections and sagittal isthmus sections | ||
+ | File:Sectioning of thyroidectomy without isthmus.svg|Short/inconspicious isthmus: The isthmus can be included in the transverse sections. | ||
+ | </gallery> | ||
+ | {{Gross processing}} | ||
{{Bottom}} | {{Bottom}} |
Revision as of 04:04, 7 January 2020
Author:
Mikael Häggström [note 1]
Fixation
Generally 10% neutral buffered formalin. Fix all thyroids at least overnight to avoid artifactual nuclear atypia.[1]
See also: General notes on fixation
Gross processing
- Weigh[1]
- Measure each lobe and isthmus in 3 dimensions, respectively.[1]
- Ink outer surface,[1] at least if malignancy is suspected.[2]:Template:Ink note
Hemithyroidecomy (lobe + isthmus) or lobectomy, including completion thyroidectomies: Use separate colors over the cut surface and the outer “capsular” surface.[notes 1]
None of the outer “capsular” surface should be inked like the cut surface.[notes 1]
Serially section the specimen at 3-4mm intervals,[3] such as follows:[1]
See also: General notes on gross processing
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 1.2 1.3 1.4 . Gross Pathology Manual By The University of Chicago Department of Pathology. Updated 2-14-19 NAC.
- ↑ Monica Dahlgren, Janne Malina, Anna Måsbäck, Otto Ljungberg. Stora utskärningen. KVAST (Swedish Society of Pathology). Retrieved on 2019-09-26.
- ↑ . THYROID. Royal College of pathologists of Australia. Retrieved on 2019-12-17.
Image sources