Difference between revisions of "Thyroid"

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{{Fixation - general notes}}
 
{{Fixation - general notes}}
 
==Gross processing==
 
==Gross processing==
===Selection and trimming===
 
 
*'''Weigh'''<ref name=chicago/>
 
*'''Weigh'''<ref name=chicago/>
 
*'''Measure''' each lobe and isthmus in 3 dimensions, respectively.<ref name=chicago/>
 
*'''Measure''' each lobe and isthmus in 3 dimensions, respectively.<ref name=chicago/>
*'''Ink''' outer surface:{{Ink note}}<ref name=chicago/>
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*'''Ink''' outer surface,<ref name=chicago/> at least if malignancy is suspected.<ref>{{Stora utskärningen}}</ref>:{{Ink note}}
<gallery mode=packed>
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<gallery>
File:Grossing of hemithyroidectomy.svg|Hemithyroidecomy (lobe + isthmus) or lobectomy, including completion thyroidectomies: Use separate colors over the cut surface and the outer “capsular” surface.<ref group="notes" name="coloring">Separate coloring allows to distinguish the thyroid margin (continuous with the other lobe) from the peripheral margin (towards soft tissues).
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File:Grossing of hemithyroidectomy.svg|Hemithyroidecomy (lobe + isthmus) or lobectomy, including completion thyroidectomies: Use separate colors over the cut surface and the outer “capsular” surface.<ref group="notes" name="coloring">Separate coloring allows to distinguish the thyroid margin (continuous with the other lobe) from the peripheral margin (towards soft tissues).</ref>
 
File:How to not gross hemithyroidectomy.svg|None of the outer “capsular” surface should be inked like the cut surface.<ref group="notes" name="coloring"/>
 
File:How to not gross hemithyroidectomy.svg|None of the outer “capsular” surface should be inked like the cut surface.<ref group="notes" name="coloring"/>
 
File:Grossing of thyroidectomy with isthmus.svg|Intact total thyroidectomy: Separate colors for each lobe and the isthmus.
 
File:Grossing of thyroidectomy with isthmus.svg|Intact total thyroidectomy: Separate colors for each lobe and the isthmus.
 
File:Grossing of thyroidectomy without isthmus.svg|If no appreciable isthmus, Separate colors for each lobe.
 
File:Grossing of thyroidectomy without isthmus.svg|If no appreciable isthmus, Separate colors for each lobe.
 
</gallery>
 
</gallery>
{{Selection and trimming}}
+
Serially '''section''' the specimen at 3-4mm intervals,<ref>{{cite web|url=https://www.rcpa.edu.au/Manuals/Macroscopic-Cut-Up-Manual/Endocrine/Thyroid|title=THYROID|website=Royal College of pathologists of Australia|accessdate=2019-12-17}}</ref> such as follows:<ref name=chicago/>
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<gallery>
 +
File:Sectioning of hemithyroidectomy.svg|Hemithyroidecomy (lobe + isthmus) or lobectomy: Include isthmic orange margins in your transverse sections.
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File:Sectioning of thyroidectomy with isthmus.svg|Intact total thyroidectomy: Transverse lobe sections and sagittal isthmus sections
 +
File:Sectioning of thyroidectomy without isthmus.svg|Short/inconspicious isthmus: The isthmus can be included in the transverse sections.
 +
</gallery>
 +
{{Gross processing}}
 
{{Bottom}}
 
{{Bottom}}

Revision as of 04:04, 7 January 2020

Author: Mikael Häggström [note 1]

Fixation

Generally 10% neutral buffered formalin. Fix all thyroids at least overnight to avoid artifactual nuclear atypia.[1]

  See also: General notes on fixation


Gross processing

  • Weigh[1]
  • Measure each lobe and isthmus in 3 dimensions, respectively.[1]
  • Ink outer surface,[1] at least if malignancy is suspected.[2]:Template:Ink note

Serially section the specimen at 3-4mm intervals,[3] such as follows:[1]

  See also: General notes on gross processing


Notes

  1. 1.0 1.1 Separate coloring allows to distinguish the thyroid margin (continuous with the other lobe) from the peripheral margin (towards soft tissues).
  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. 1.0 1.1 1.2 1.3 1.4 . Gross Pathology Manual By The University of Chicago Department of Pathology. Updated 2-14-19 NAC.
  2. Monica Dahlgren, Janne Malina, Anna Måsbäck, Otto Ljungberg. Stora utskärningen. KVAST (Swedish Society of Pathology). Retrieved on 2019-09-26.
  3. . THYROID. Royal College of pathologists of Australia. Retrieved on 2019-12-17.

Image sources