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→Selection and trimming: Maintain
[[File:Cutting of uneven lumpectomy.jpg|thumb|240px|Cut a lumpectomy in the direction that gives the shortest distance from margin to margin. If a lumpectomy is uneven as shown, cut so that the first and last slice become wedge shaped (because these will later be cut further, perpendicularly to the margin), avoiding a wedge-shape for remaining slices.]]
*'''Serially section''' the specimen.
:*When performing '''triage''' of fresh lumpectomies, generally make slices 1.1 to 1.5 cm thick. When laid down and flattened, this is generally thin enough to allow for fixation over at least 6 hours, and thick enough to be further cut into 2 or 3 slices after fixation; Note the direction of up/down on each such thick slice so that the relative orientation of the thinner slices thereof is maintained. Slices with solid tumors are cut somewhat thinner since they won't flatten as much when laid down.
:*When selecting tissue for submission after fixation, make 3-4 mm thick '''slices'''.<ref name=Roychowdhury/>
*'''Inspect''' for any grossly visible lesions. If found, measure at least the greatest dimension of the lesion on the slice where it appears largest. {{Moderate-begin}}Also compare the greatest gross measurement (including any palpated one) with the greatest measurement at previous imaging, and note if it confers a staging discrepancy between imaging and gross dimensions, with cutoffs at 0.1 cm, 0.5 cm, 1.0 cm, 2.0 cm, and 5 cm.{{Moderate-end}}
