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Breast biopsy or excision

1,047 bytes added, 11:09, 24 February 2022
| {{Moderate-begin}}The specimen is received fresh and consists of{{Moderate-end}} an irregular fragment of yellow tan fibrofatty tissue measuring 4.0 x 2.8 x 2.0 cm. {{Moderate-begin}}The specimen is oriented with two sutures and{{Moderate-end}} the surgical margins are inked as follows: superior-blue, inferior-green, medial-red, lateral-yellow, anterior-orange, and posterior-black. {{Finding-begin}}A radioactive seed is embedded in the tissue.{{Finding-end}} The tissue is serially sectioned {{Finding-begin}}to reveal a tan-gray, spiculated, indurated mass measuring _cm in greatest dimension. The mass is located _cm from the nearest (<<superior, inferior etc>>) margin. {{Moderate-begin}}The specimen is entirely submitted in sequential sections from medial to lateral in 10 cassettes. The medial and lateral margins are submitted as perpendicular sections.{{Moderate-end}} The specimen was procured at _AM/PM on _/_/2020. The specimen was placed in formalin at _AM/PM on _/_/2020.
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===Lymph nodes===
When lymph nodes are submitted together with a biopsy or excision of a suspected or previously confirmed [[invasive lobular carcinoma]] (but not necessarily invasive carcinoma with lobular features), generally put the lymph node specimen through H&E processing at a relative rush. If you don't see any involvement on the H&E stain, order immunostain for CK AE1/AE3 in order to visualize otherwise occult lymph node involvement. The rushing of the lymph node samples allows you to have the immunostained slides by a similar time as the rest of the case.<ref name="pmid12610108">{{cite journal| author=Chandler IP, Oommen R, Lawson CW| title=Invasive lobular carcinoma and cytokeratin immunohistochemistry: an audit. | journal=J Clin Pathol | year= 2003 | volume= 56 | issue= 3 | pages= 240 | pmid=12610108 | doi=10.1136/jcp.56.3.240 | pmc=1769908 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12610108 }} </ref>
{{further|Lymph node|linebreak=yes}}
==Staining==

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