Cervical cytology - Revision history

Mikael Häggström: /* Main conditions to exclude or confirm */ Tip

2026-07-23T14:35:34Z

Main conditions to exclude or confirm: Tip

← Older revision		Revision as of 10:35, 23 July 2026
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	==Main conditions to exclude or confirm==		==Main conditions to exclude or confirm==
	'''Squamous atypia''', seen mainly as cells with increased nucleus/cytoplasm ratio, nuclear hyperchromasia and irregular nuclear outline.		'''Squamous atypia''', seen mainly as cells with increased nucleus/cytoplasm ratio, nuclear hyperchromasia and irregular nuclear outline.

			If the slide has been previously marked by a cytotechnologist or other previewer, grade the marked cells first. Then, you only need to look for worse findings on the rest of the slide.
	<gallery mode=packed heights=220>		<gallery mode=packed heights=220>
	File:Atipia de células escamosas (ASCUS, ASC) (9392112063).jpg\|'''Atypical squamous cells of undetermined significance (ASCUS)''', with only few slightly atypical cells		File:Atipia de células escamosas (ASCUS, ASC) (9392112063).jpg\|'''Atypical squamous cells of undetermined significance (ASCUS)''', with only few slightly atypical cells
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	If you are uncertain of the degree of dysplasia, it can be useful to look up how much difference it will likely make for the management of the patient. You may make an Internet search for the management of abnormal cervical screening in your region (such as [https://app.asccp.org/ The ASCCP tool] for management in the US). A change from close follow-up to colposcopy is not that big of a deal, but if one of the alternatives will lead to a diagnostic excision, make sure that the case is looked upon by commensurate expertise.		If you are uncertain of the degree of dysplasia, it can be useful to look up how much difference it will likely make for the management of the patient. You may make an Internet search for the management of abnormal cervical screening in your region (such as [https://app.asccp.org/ The ASCCP tool] for management in the US). A change from close follow-up to colposcopy is not that big of a deal, but if one of the alternatives will lead to a diagnostic excision, make sure that the case is looked upon by commensurate expertise.
	<noinclude>		<noinclude>

	==Other findings==		==Other findings==
	<gallery mode=packed heights=220>		<gallery mode=packed heights=220>

Mikael Häggström:

2022-12-04T15:42:11Z

← Older revision		Revision as of 11:42, 4 December 2022
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	{{Top		<noinclude>{{Top
	\|author1=[[User:Mikael Häggström\|Mikael Häggström]]		\|author1=[[User:Mikael Häggström\|Mikael Häggström]]
	\|author2=		\|author2=
	}}		}}
	~~<noinclude>~~'''[[Cytology]]''' of the '''[[cervix]]''':</noinclude>		'''[[Cytology]]''' of the '''[[cervix]]''':</noinclude>
	==Clinical information==		==Clinical information==
	It is not necessary to look through more than readily available reports from previous cervical cytologies.		It is not necessary to look through more than readily available reports from previous cervical cytologies.
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	:Negative for intraepithelial lesion or malignancy (NILM).		:Negative for intraepithelial lesion or malignancy (NILM).
	\|}		\|}
	{{Bottom}}		<noinclude>{{Bottom}}</noinclude>

Mikael Häggström: Clinical implication

2022-10-01T15:43:32Z

Clinical implication

← Older revision		Revision as of 11:43, 1 October 2022
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	File:Glycogenated cervical squamous cells.tif\|Distinguish HPV-changes from '''glycogenated''' squamous cells. Glycogen confers a yellowish color to the cytoplasm. It can look like the perinuclear cavitation of koilocytes, but has more rounded edges.		File:Glycogenated cervical squamous cells.tif\|Distinguish HPV-changes from '''glycogenated''' squamous cells. Glycogen confers a yellowish color to the cytoplasm. It can look like the perinuclear cavitation of koilocytes, but has more rounded edges.
	</gallery>		</gallery>
			===Clinical implication===
			If you are uncertain of the degree of dysplasia, it can be useful to look up how much difference it will likely make for the management of the patient. You may make an Internet search for the management of abnormal cervical screening in your region (such as [https://app.asccp.org/ The ASCCP tool] for management in the US). A change from close follow-up to colposcopy is not that big of a deal, but if one of the alternatives will lead to a diagnostic excision, make sure that the case is looked upon by commensurate expertise.
	<noinclude>		<noinclude>

	==Other findings==		==Other findings==
	<gallery mode=packed heights=220>		<gallery mode=packed heights=220>

Mikael Häggström: /* Main conditions to exclude or confirm */ Expanded

2022-09-30T22:08:26Z

Main conditions to exclude or confirm: Expanded

← Older revision		Revision as of 18:08, 30 September 2022
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	File:ThinPrep Pap smear HPV.jpeg\|LSIL and '''changes consistent with human papillomavirus''' (HPV), which is the presence of koilocytes, which show perinuclear cavitation, binucleation, nuclear hyperchromasia, and nuclear enlargement.		File:ThinPrep Pap smear HPV.jpeg\|LSIL and '''changes consistent with human papillomavirus''' (HPV), which is the presence of koilocytes, which show perinuclear cavitation, binucleation, nuclear hyperchromasia, and nuclear enlargement.
	</gallery>		</gallery>
	[[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|~~300px~~\|Cytopathology of squamous cell carcinoma, nonkeratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]		[[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|350px\|Cytopathology of squamous cell carcinoma, nonkeratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain. Necrotic debris (dirty background) is a feature that generally makes a HSIL case "suspicious for invasive squamous cell carcinoma".<ref name="pmid34345247">{{cite journal\| author=Alrajjal A, Pansare V, Choudhury MSR, Khan MYA, Shidham VB\| title=Squamous intraepithelial lesions (SIL: LSIL, HSIL, ASCUS, ASC-H, LSIL-H) of Uterine Cervix and Bethesda System. \| journal=Cytojournal \| year= 2021 \| volume= 18 \| issue= \| pages= 16 \| pmid=34345247 \| doi=10.25259/Cytojournal_24_2021 \| pmc=8326095 \| url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=34345247 }} </ref> In contrast to the more distinct keratinizing variant, these findings are overall less specific, and most can be seen in other cancers such as [[adenocarcinoma]] as well (which, however, tends to have fine chromatin)<ref>{{cite web\|url=https://www.pathologyoutlines.com/topic/lungtumoradenocarcinoma.html\|title=Adenocarcinoma overview\|website=Pathology Outlines\|author=Authors: Caroline I.M. Underwood, M.D., Alexis Musick, B.S., Carolyn Glass, M.D., Ph.D.}} Last staff update: 19 July 2022</ref>]]
	<gallery mode=packed heights=220>		<gallery mode=packed heights=220>
	File:Glycogenated cervical squamous cells.tif\|Distinguish HPV-changes from '''glycogenated''' squamous cells. Glycogen confers a yellowish color to the cytoplasm. It can look like the perinuclear cavitation of koilocytes, but has more rounded edges.		File:Glycogenated cervical squamous cells.tif\|Distinguish HPV-changes from '''glycogenated''' squamous cells. Glycogen confers a yellowish color to the cytoplasm. It can look like the perinuclear cavitation of koilocytes, but has more rounded edges.

Mikael Häggström: /* Main conditions to exclude or confirm */ Format

2022-09-29T12:00:40Z

Main conditions to exclude or confirm: Format

← Older revision		Revision as of 08:00, 29 September 2022
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	File:Cytopathology of low-grade squamous intraepithelial lesion (LSIL).png\|'''Low-grade squamous intraepithelial lesion (LSIL)''', here compared to an unremarkable intermediate squamous cell.		File:Cytopathology of low-grade squamous intraepithelial lesion (LSIL).png\|'''Low-grade squamous intraepithelial lesion (LSIL)''', here compared to an unremarkable intermediate squamous cell.
	File:Cytology of High-Grade SIL, ThinPrep.jpg\|'''High-grade squamous intraepithelial lesion (HSIL)''', showing even more prominent features, and decreased cytoplasm, causing a high nuclear/cytoplasmic ratio.		File:Cytology of High-Grade SIL, ThinPrep.jpg\|'''High-grade squamous intraepithelial lesion (HSIL)''', showing even more prominent features, and decreased cytoplasm, causing a high nuclear/cytoplasmic ratio.
			File:Cytopathology of keratinizing squamous cell carcinoma.png\|Cytopathology of '''squamous cell carcinoma, keratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.
			File:ThinPrep Pap smear HPV.jpeg\|LSIL and '''changes consistent with human papillomavirus''' (HPV), which is the presence of koilocytes, which show perinuclear cavitation, binucleation, nuclear hyperchromasia, and nuclear enlargement.
	</gallery>		</gallery>
	{\|		[[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|300px\|Cytopathology of squamous cell carcinoma, nonkeratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]
	\| [[File:Cytopathology of keratinizing squamous cell carcinoma.png\|thumb\|270px\|left\|Cytopathology of squamous cell carcinoma, keratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]
	\| [[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|300px~~\|left~~\|Cytopathology of squamous cell carcinoma, nonkeratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]
	\|}
	<gallery mode=packed heights=220>		<gallery mode=packed heights=220>
	File:ThinPrep Pap smear HPV.jpeg\|LSIL and '''changes consistent with human papillomavirus''' (HPV), which is the presence of koilocytes, which show perinuclear cavitation, binucleation, nuclear hyperchromasia, and nuclear enlargement.
	File:Glycogenated cervical squamous cells.tif\|Distinguish HPV-changes from '''glycogenated''' squamous cells. Glycogen confers a yellowish color to the cytoplasm. It can look like the perinuclear cavitation of koilocytes, but has more rounded edges.		File:Glycogenated cervical squamous cells.tif\|Distinguish HPV-changes from '''glycogenated''' squamous cells. Glycogen confers a yellowish color to the cytoplasm. It can look like the perinuclear cavitation of koilocytes, but has more rounded edges.
	</gallery>		</gallery>

Mikael Häggström: /* Main conditions to exclude or confirm */ Enlarged

2022-09-28T22:36:17Z

Main conditions to exclude or confirm: Enlarged

← Older revision		Revision as of 18:36, 28 September 2022
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	</gallery>		</gallery>
	{\|		{\|
	\| [[File:Cytopathology of keratinizing squamous cell carcinoma.png\|thumb\|~~250px~~\|left\|Cytopathology of squamous cell carcinoma, keratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]		\| [[File:Cytopathology of keratinizing squamous cell carcinoma.png\|thumb\|270px\|left\|Cytopathology of squamous cell carcinoma, keratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]
	\| [[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|~~280px~~\|left\|Cytopathology of squamous cell carcinoma, nonkeratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]		\| [[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|300px\|left\|Cytopathology of squamous cell carcinoma, nonkeratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]
	\|}		\|}
	<gallery mode=packed heights=220>		<gallery mode=packed heights=220>

Mikael Häggström: /* Main conditions to exclude or confirm */ Format

2022-09-28T22:35:11Z

Main conditions to exclude or confirm: Format

← Older revision		Revision as of 18:35, 28 September 2022
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	File:Cytology of High-Grade SIL, ThinPrep.jpg\|'''High-grade squamous intraepithelial lesion (HSIL)''', showing even more prominent features, and decreased cytoplasm, causing a high nuclear/cytoplasmic ratio.		File:Cytology of High-Grade SIL, ThinPrep.jpg\|'''High-grade squamous intraepithelial lesion (HSIL)''', showing even more prominent features, and decreased cytoplasm, causing a high nuclear/cytoplasmic ratio.
	</gallery>		</gallery>
	~~<gallery mode=packed heights=300>~~		{\|
	File:Cytopathology of keratinizing squamous cell carcinoma.png\|~~'''Squamous~~ cell carcinoma, keratinizing variant~~'''~~, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.		\| [[File:Cytopathology of keratinizing squamous cell carcinoma.png\|thumb\|250px\|left\|Cytopathology of squamous cell carcinoma, keratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]
	File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|~~'''~~Cytopathology of squamous cell carcinoma, nonkeratinizing variant~~'''~~, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.		\| [[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|280px\|left\|Cytopathology of squamous cell carcinoma, nonkeratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]
	~~</gallery>~~		\|}
	<gallery mode=packed heights=220>		<gallery mode=packed heights=220>
	File:ThinPrep Pap smear HPV.jpeg\|LSIL and '''changes consistent with human papillomavirus''' (HPV), which is the presence of koilocytes, which show perinuclear cavitation, binucleation, nuclear hyperchromasia, and nuclear enlargement.		File:ThinPrep Pap smear HPV.jpeg\|LSIL and '''changes consistent with human papillomavirus''' (HPV), which is the presence of koilocytes, which show perinuclear cavitation, binucleation, nuclear hyperchromasia, and nuclear enlargement.

Mikael Häggström: /* Main conditions to exclude or confirm */ Format

2022-09-28T22:23:44Z

Main conditions to exclude or confirm: Format

← Older revision		Revision as of 18:23, 28 September 2022
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	</gallery>		</gallery>
	<gallery mode=packed heights=300>		<gallery mode=packed heights=300>
	[[File:Cytopathology of keratinizing squamous cell carcinoma.png~~\|thumb\|330px~~\|'''Squamous cell carcinoma, keratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]		File:Cytopathology of keratinizing squamous cell carcinoma.png\|'''Squamous cell carcinoma, keratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.
	[[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png~~\|thumb\|330px~~\|'''Cytopathology of squamous cell carcinoma, nonkeratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]		File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|'''Cytopathology of squamous cell carcinoma, nonkeratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.
	</gallery>		</gallery>
	<gallery mode=packed heights=220>		<gallery mode=packed heights=220>

Mikael Häggström: /* Main conditions to exclude or confirm */ Format

2022-09-28T22:23:05Z

Main conditions to exclude or confirm: Format

← Older revision		Revision as of 18:23, 28 September 2022
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	==Main conditions to exclude or confirm==		==Main conditions to exclude or confirm==
	'''Squamous atypia''', seen mainly as cells with increased nucleus/cytoplasm ratio, nuclear hyperchromasia and irregular nuclear outline.		'''Squamous atypia''', seen mainly as cells with increased nucleus/cytoplasm ratio, nuclear hyperchromasia and irregular nuclear outline.
	[[File:Cytopathology of keratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Squamous cell carcinoma, keratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]		<gallery mode=packed heights=220>
	[[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Cytopathology of squamous cell carcinoma, nonkeratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]
	<gallery mode=packed heights=~~200~~>
	File:Atipia de células escamosas (ASCUS, ASC) (9392112063).jpg\|'''Atypical squamous cells of undetermined significance (ASCUS)''', with only few slightly atypical cells		File:Atipia de células escamosas (ASCUS, ASC) (9392112063).jpg\|'''Atypical squamous cells of undetermined significance (ASCUS)''', with only few slightly atypical cells
	File:Cytopathology of low-grade squamous intraepithelial lesion (LSIL).png\|'''Low-grade squamous intraepithelial lesion (LSIL)''', here compared to an unremarkable intermediate squamous cell.		File:Cytopathology of low-grade squamous intraepithelial lesion (LSIL).png\|'''Low-grade squamous intraepithelial lesion (LSIL)''', here compared to an unremarkable intermediate squamous cell.
	File:Cytology of High-Grade SIL, ThinPrep.jpg\|'''High-grade squamous intraepithelial lesion (HSIL)''', showing even more prominent features, and decreased cytoplasm, causing a high nuclear/cytoplasmic ratio.		File:Cytology of High-Grade SIL, ThinPrep.jpg\|'''High-grade squamous intraepithelial lesion (HSIL)''', showing even more prominent features, and decreased cytoplasm, causing a high nuclear/cytoplasmic ratio.
			</gallery>
			<gallery mode=packed heights=300>
			[[File:Cytopathology of keratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Squamous cell carcinoma, keratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]
			[[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Cytopathology of squamous cell carcinoma, nonkeratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]
			</gallery>
			<gallery mode=packed heights=220>
	File:ThinPrep Pap smear HPV.jpeg\|LSIL and '''changes consistent with human papillomavirus''' (HPV), which is the presence of koilocytes, which show perinuclear cavitation, binucleation, nuclear hyperchromasia, and nuclear enlargement.		File:ThinPrep Pap smear HPV.jpeg\|LSIL and '''changes consistent with human papillomavirus''' (HPV), which is the presence of koilocytes, which show perinuclear cavitation, binucleation, nuclear hyperchromasia, and nuclear enlargement.
	File:Glycogenated cervical squamous cells.tif\|Distinguish HPV-changes from '''glycogenated''' squamous cells. Glycogen confers a yellowish color to the cytoplasm. It can look like the perinuclear cavitation of koilocytes, but has more rounded edges.		File:Glycogenated cervical squamous cells.tif\|Distinguish HPV-changes from '''glycogenated''' squamous cells. Glycogen confers a yellowish color to the cytoplasm. It can look like the perinuclear cavitation of koilocytes, but has more rounded edges.

Mikael Häggström: /* Main conditions to exclude or confirm */ Sized

2022-09-28T22:21:12Z

Main conditions to exclude or confirm: Sized

← Older revision		Revision as of 18:21, 28 September 2022
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	[[File:Cytopathology of keratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Squamous cell carcinoma, keratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]		[[File:Cytopathology of keratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Squamous cell carcinoma, keratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]
	[[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Cytopathology of squamous cell carcinoma, nonkeratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]		[[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Cytopathology of squamous cell carcinoma, nonkeratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]
	<gallery mode=packed heights=~~220~~>		<gallery mode=packed heights=200>
	File:Atipia de células escamosas (ASCUS, ASC) (9392112063).jpg\|'''Atypical squamous cells of undetermined significance (ASCUS)''', with only few slightly atypical cells		File:Atipia de células escamosas (ASCUS, ASC) (9392112063).jpg\|'''Atypical squamous cells of undetermined significance (ASCUS)''', with only few slightly atypical cells
	File:Cytopathology of low-grade squamous intraepithelial lesion (LSIL).png\|'''Low-grade squamous intraepithelial lesion (LSIL)''', here compared to an unremarkable intermediate squamous cell.		File:Cytopathology of low-grade squamous intraepithelial lesion (LSIL).png\|'''Low-grade squamous intraepithelial lesion (LSIL)''', here compared to an unremarkable intermediate squamous cell.

← Older revision		Revision as of 08:00, 29 September 2022
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	File:Cytopathology of low-grade squamous intraepithelial lesion (LSIL).png\|'''Low-grade squamous intraepithelial lesion (LSIL)''', here compared to an unremarkable intermediate squamous cell.		File:Cytopathology of low-grade squamous intraepithelial lesion (LSIL).png\|'''Low-grade squamous intraepithelial lesion (LSIL)''', here compared to an unremarkable intermediate squamous cell.
	File:Cytology of High-Grade SIL, ThinPrep.jpg\|'''High-grade squamous intraepithelial lesion (HSIL)''', showing even more prominent features, and decreased cytoplasm, causing a high nuclear/cytoplasmic ratio.		File:Cytology of High-Grade SIL, ThinPrep.jpg\|'''High-grade squamous intraepithelial lesion (HSIL)''', showing even more prominent features, and decreased cytoplasm, causing a high nuclear/cytoplasmic ratio.
			File:Cytopathology of keratinizing squamous cell carcinoma.png\|Cytopathology of '''squamous cell carcinoma, keratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.
			File:ThinPrep Pap smear HPV.jpeg\|LSIL and '''changes consistent with human papillomavirus''' (HPV), which is the presence of koilocytes, which show perinuclear cavitation, binucleation, nuclear hyperchromasia, and nuclear enlargement.
	</gallery>		</gallery>
	{\|		[[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|300px\|Cytopathology of squamous cell carcinoma, nonkeratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]
	\| [[File:Cytopathology of keratinizing squamous cell carcinoma.png\|thumb\|270px\|left\|Cytopathology of squamous cell carcinoma, keratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]
	\| [[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|300px~~\|left~~\|Cytopathology of squamous cell carcinoma, nonkeratinizing variant, with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]
	\|}
	<gallery mode=packed heights=220>		<gallery mode=packed heights=220>
	File:ThinPrep Pap smear HPV.jpeg\|LSIL and '''changes consistent with human papillomavirus''' (HPV), which is the presence of koilocytes, which show perinuclear cavitation, binucleation, nuclear hyperchromasia, and nuclear enlargement.
	File:Glycogenated cervical squamous cells.tif\|Distinguish HPV-changes from '''glycogenated''' squamous cells. Glycogen confers a yellowish color to the cytoplasm. It can look like the perinuclear cavitation of koilocytes, but has more rounded edges.		File:Glycogenated cervical squamous cells.tif\|Distinguish HPV-changes from '''glycogenated''' squamous cells. Glycogen confers a yellowish color to the cytoplasm. It can look like the perinuclear cavitation of koilocytes, but has more rounded edges.
	</gallery>		</gallery>

← Older revision		Revision as of 18:21, 28 September 2022
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	[[File:Cytopathology of keratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Squamous cell carcinoma, keratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]		[[File:Cytopathology of keratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Squamous cell carcinoma, keratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image from National Cancer Institute (Public Domain)</ref> Pap stain.]]
	[[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Cytopathology of squamous cell carcinoma, nonkeratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]		[[File:Cytopathology of nonkeratinizing squamous cell carcinoma.png\|thumb\|330px\|'''Cytopathology of squamous cell carcinoma, nonkeratinizing variant''', with typical features.<ref>- Image annotated by Mikael Häggström<br>- Reference for entries: {{cite web\|url=https://www.pathologyoutlines.com/topic/cervixSCC.html\|title=Cervix - Squamous cell carcinoma and variants\|author=Gulisa Turashvili, M.D., Ph.D.\|website=Pathology Outlines}} Last author update: 24 September 2020. Last staff update: 4 April 2022.<br>- Source image by Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim (Creative Commons Attribution 2.0 Generic license.)</ref> Pap stain.]]
	<gallery mode=packed heights=~~220~~>		<gallery mode=packed heights=200>
	File:Atipia de células escamosas (ASCUS, ASC) (9392112063).jpg\|'''Atypical squamous cells of undetermined significance (ASCUS)''', with only few slightly atypical cells		File:Atipia de células escamosas (ASCUS, ASC) (9392112063).jpg\|'''Atypical squamous cells of undetermined significance (ASCUS)''', with only few slightly atypical cells
	File:Cytopathology of low-grade squamous intraepithelial lesion (LSIL).png\|'''Low-grade squamous intraepithelial lesion (LSIL)''', here compared to an unremarkable intermediate squamous cell.		File:Cytopathology of low-grade squamous intraepithelial lesion (LSIL).png\|'''Low-grade squamous intraepithelial lesion (LSIL)''', here compared to an unremarkable intermediate squamous cell.