Liver - Revision history

Mikael Häggström: /* Microscopic evaluation */ Format

2023-10-27T19:18:26Z

Microscopic evaluation: Format

← Older revision		Revision as of 15:18, 27 October 2023
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	==Microscopic evaluation==		==Microscopic evaluation==
	[[File:Histopathology of liver zones.jpg\|thumb\|Pathologies can be topographically classified by liver zones. P: portal tract. V: central vein.]]		[[File:Histopathology of liver zones.jpg\|thumb\|Pathologies can be topographically classified by liver zones. P: portal tract. V: central vein.]]
	A general screening includes:		A general screening includes (with further information in sections below):
	*Looking at the '''referral/requisition form''' {{Moderate-begin}}and looking at the medical records{{Moderate-end}} for particular conditions to look for or evaluate. {{Moderate-begin}}Perform a severity grading of '''previously known liver diseases'''.{{Moderate-end}}		*Looking at the '''referral/requisition form''' {{Moderate-begin}}and looking at the medical records{{Moderate-end}} for particular conditions to look for or evaluate. {{Moderate-begin}}Perform a severity grading of '''previously known liver diseases'''.{{Moderate-end}}
	:*Commonly, this includes to quantify any '''cirrhosis''', at least if the patient had alcohol abuse.		:*Commonly, this includes to quantify any '''cirrhosis''', at least if the patient had alcohol abuse.
			:*'''Steatosis''' is also common.
			*Signs of '''acute liver failure'''.
			*Signs of '''malignancy'''. If a tumor is found: {{Further\|Liver tumor\|linebreak=no}}
			*Signs of '''congestive hepatopathy''' (indicating heart failure).
			*Signs of '''inflammation''' at least around the portal triads.

			===Cirrhosis===
	<gallery mode=packed heights=170>		<gallery mode=packed heights=170>
	File:Histopathology of steatohepatitis with mild fibrosis in the form of fibrous expansion (van Gieson).jpg\|Steatohepatitis with '''mild fibrosis''' (van Gieson's stain).<ref name="BoydCain2020"/>		File:Histopathology of steatohepatitis with mild fibrosis in the form of fibrous expansion (van Gieson).jpg\|Steatohepatitis with '''mild fibrosis''' (van Gieson's stain).<ref name="BoydCain2020"/>
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	</gallery>		</gallery>
	{{Further\|Cirrhosis}}		{{Further\|Cirrhosis}}
	~~:*'''Steatosis''' is also common, (see section below).~~
	*Signs of '''acute liver failure'''. ''Further information in section below.''
	*Signs of '''malignancy'''. If a tumor is found: {{Further\|Liver tumor\|linebreak=no}}
	*Signs of '''congestive hepatopathy''' (indicating heart failure). ''Further information in section below.''
	*Signs of '''inflammation''' at least around the portal triads.

	===Steatosis===		===Steatosis===
	At least classify steatosis by severity:		At least classify steatosis by severity:

Mikael Häggström: Comprehensive

2023-04-05T21:35:47Z

Comprehensive

← Older revision		Revision as of 17:35, 5 April 2023
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	[[File:Histopathology of liver zones.jpg\|thumb\|Pathologies can be topographically classified by liver zones. P: portal tract. V: central vein.]]		[[File:Histopathology of liver zones.jpg\|thumb\|Pathologies can be topographically classified by liver zones. P: portal tract. V: central vein.]]
	A general screening includes:		A general screening includes:
	*Looking at the '''referral/requisition form''' {{Moderate-begin}}and looking at the medical records{{Moderate-end}} for particular conditions to look for or evaluate. ~~Generally, perform~~ a severity grading of '''previously known liver diseases'''.		*Looking at the '''referral/requisition form''' {{Moderate-begin}}and looking at the medical records{{Moderate-end}} for particular conditions to look for or evaluate. {{Moderate-begin}}Perform a severity grading of '''previously known liver diseases'''.{{Moderate-end}}
	:*Commonly, this includes to quantify any '''cirrhosis''', at least if the patient had alcohol abuse.		:*Commonly, this includes to quantify any '''cirrhosis''', at least if the patient had alcohol abuse.
	<gallery mode=packed heights=170>		<gallery mode=packed heights=170>
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	===Report===		===Report===
	*~~At least if the patient had alcohol abuse, a quantification~~ of ~~cirrhosis~~.		*Presence of any liver disease
	*~~Optionally, even~~ absence of hepatitis, malignancy, congestive hepatopathy and/or steatosis.		:*{{Moderate-begin}}Quantification of its severity.{{Moderate-end}}
			*{{Comprehensive-begin}}Even absence of hepatitis, malignancy, congestive hepatopathy and/or steatosis.{{Comprehensive-end}}

	{{Bottom}}		{{Bottom}}

Mikael Häggström: /* Microscopic evaluation */ Merged

2023-04-05T18:18:54Z

Microscopic evaluation: Merged

← Older revision		Revision as of 14:18, 5 April 2023
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	[[File:Histopathology of liver zones.jpg\|thumb\|Pathologies can be topographically classified by liver zones. P: portal tract. V: central vein.]]		[[File:Histopathology of liver zones.jpg\|thumb\|Pathologies can be topographically classified by liver zones. P: portal tract. V: central vein.]]
	A general screening includes:		A general screening includes:
	*Looking at the '''referral/requisition form''' {{Moderate-begin}}and looking at the medical records{{Moderate-end}} for particular conditions to look for or evaluate.		*Looking at the '''referral/requisition form''' {{Moderate-begin}}and looking at the medical records{{Moderate-end}} for particular conditions to look for or evaluate. Generally, perform a severity grading of '''previously known liver diseases'''.
	*A severity grading of '''previously known liver diseases'''.
	:*Commonly, this includes to quantify any '''cirrhosis''', at least if the patient had alcohol abuse.		:*Commonly, this includes to quantify any '''cirrhosis''', at least if the patient had alcohol abuse.
	<gallery mode=packed heights=170>		<gallery mode=packed heights=170>

Mikael Häggström: /* Microscopic evaluation */ Particularly important

2023-04-05T18:17:55Z

Microscopic evaluation: Particularly important

← Older revision		Revision as of 14:17, 5 April 2023
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	[[File:Histopathology of liver zones.jpg\|thumb\|Pathologies can be topographically classified by liver zones. P: portal tract. V: central vein.]]		[[File:Histopathology of liver zones.jpg\|thumb\|Pathologies can be topographically classified by liver zones. P: portal tract. V: central vein.]]
	A general screening includes:		A general screening includes:
			*Looking at the '''referral/requisition form''' {{Moderate-begin}}and looking at the medical records{{Moderate-end}} for particular conditions to look for or evaluate.
	*A severity grading of '''previously known liver diseases'''.		*A severity grading of '''previously known liver diseases'''.
	:*Commonly, this includes to quantify any '''cirrhosis''', at least if the patient had alcohol abuse.		:*Commonly, this includes to quantify any '''cirrhosis''', at least if the patient had alcohol abuse.

Mikael Häggström: /* Hemosiderin */ +Iron stain

2022-10-18T15:42:43Z

Hemosiderin: +Iron stain

← Older revision		Revision as of 11:42, 18 October 2022
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	<gallery mode=packed heights=180>		<gallery mode=packed heights=180>
	File:Kupffer cell with hemosiderin and hepatocyte with lipofuscin.jpg\|Look for Kupffer cells with significant '''hemosiderin deposition''' (shown next to a hepatocyte with lipofuscin pigment.		File:Kupffer cell with hemosiderin and hepatocyte with lipofuscin.jpg\|Look for Kupffer cells with significant '''hemosiderin deposition''' (shown next to a hepatocyte with lipofuscin pigment.
	File:Histology of hepatocyte lipofuscin.jpg\|Hepatocyte '''lipofuscin''' is of no real pathologic importance and does not warrant a mention in the report.<ref>{{cite web\|url=https://webpath.med.utah.edu/LIVEHTML/LIVER019.html\|title=The Internet Pathology Laboratory for Medical Education\|website=The University of Utah Eccles Health Sciences Library\|accessdate=2020-12-18}}</ref>		File:Kupffer cell with hemosiderin and hepatocyte with lipofuscin, iron stain.jpg\|Iron stain can highlight the '''hemosiderin''' (blue stain) in unclear cases.
			File:Histology of hepatocyte lipofuscin.jpg\|Hepatocyte '''lipofuscin''' alone is of no real pathologic importance and does not warrant a mention in the report.<ref>{{cite web\|url=https://webpath.med.utah.edu/LIVEHTML/LIVER019.html\|title=The Internet Pathology Laboratory for Medical Education\|website=The University of Utah Eccles Health Sciences Library\|accessdate=2020-12-18}}</ref>
	</gallery>		</gallery>

Mikael Häggström: /* Common normal findings */ Expanded

2022-10-18T15:30:14Z

Common normal findings: Expanded

← Older revision		Revision as of 11:30, 18 October 2022
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	*Typical findings of '''chronic hepatic congestion''' are atrophy of hepatocytes in zone 3, perisinusoidal edema, thrombosis and hemorrhage. Chronic congestion typically displays perivenous and perisinusoidal fibrosis, with fibrous septa that bridge central hepatic veins. In contrast, other causes of distortion and cirrhosis typically have fibrous septa predominantly between portal triads. However, nonalcoholic steatohepatitis also may show perisinusoidal fibrosis in early stages; in later stages, the fibrosis tends to be in the portal triad. Cirrhosis develops in the final stages of congestive hepatopathy. Regenerating hepatocytes tend to grow in a sleevelike pattern along portal tracts, resulting in a nodular liver with preserved portal triads and obliterated or fibrosed hepatic veins, a pattern called "reverse lobulation". This pattern can also be seen in venous obstruction due to Budd-Chiari syndrome.<ref name="WellsFenstad2016">{{cite journal\|last1=Wells\|first1=Michael L.\|last2=Fenstad\|first2=Eric R.\|last3=Poterucha\|first3=Joseph T.\|last4=Hough\|first4=David M.\|last5=Young\|first5=Phillip M.\|last6=Araoz\|first6=Philip A.\|last7=Ehman\|first7=Richard L.\|last8=Venkatesh\|first8=Sudhakar K.\|title=Imaging Findings of Congestive Hepatopathy\|journal=RadioGraphics\|volume=36\|issue=4\|year=2016\|pages=1024–1037\|issn=0271-5333\|doi=10.1148/rg.2016150207}}</ref>		*Typical findings of '''chronic hepatic congestion''' are atrophy of hepatocytes in zone 3, perisinusoidal edema, thrombosis and hemorrhage. Chronic congestion typically displays perivenous and perisinusoidal fibrosis, with fibrous septa that bridge central hepatic veins. In contrast, other causes of distortion and cirrhosis typically have fibrous septa predominantly between portal triads. However, nonalcoholic steatohepatitis also may show perisinusoidal fibrosis in early stages; in later stages, the fibrosis tends to be in the portal triad. Cirrhosis develops in the final stages of congestive hepatopathy. Regenerating hepatocytes tend to grow in a sleevelike pattern along portal tracts, resulting in a nodular liver with preserved portal triads and obliterated or fibrosed hepatic veins, a pattern called "reverse lobulation". This pattern can also be seen in venous obstruction due to Budd-Chiari syndrome.<ref name="WellsFenstad2016">{{cite journal\|last1=Wells\|first1=Michael L.\|last2=Fenstad\|first2=Eric R.\|last3=Poterucha\|first3=Joseph T.\|last4=Hough\|first4=David M.\|last5=Young\|first5=Phillip M.\|last6=Araoz\|first6=Philip A.\|last7=Ehman\|first7=Richard L.\|last8=Venkatesh\|first8=Sudhakar K.\|title=Imaging Findings of Congestive Hepatopathy\|journal=RadioGraphics\|volume=36\|issue=4\|year=2016\|pages=1024–1037\|issn=0271-5333\|doi=10.1148/rg.2016150207}}</ref>

	===~~Common normal findings~~===		===Hemosiderin===
	<gallery mode=packed>		<gallery mode=packed heights=180>
	File:Histology of hepatocyte lipofuscin.jpg\|Hepatocyte '''lipofuscin''', is of no real pathologic importance and does not warrant a mention in the report.<ref>{{cite web\|url=https://webpath.med.utah.edu/LIVEHTML/LIVER019.html\|title=The Internet Pathology Laboratory for Medical Education\|website=The University of Utah Eccles Health Sciences Library\|accessdate=2020-12-18}}</ref>		File:Kupffer cell with hemosiderin and hepatocyte with lipofuscin.jpg\|Look for Kupffer cells with significant '''hemosiderin deposition''' (shown next to a hepatocyte with lipofuscin pigment.
			File:Histology of hepatocyte lipofuscin.jpg\|Hepatocyte '''lipofuscin''' is of no real pathologic importance and does not warrant a mention in the report.<ref>{{cite web\|url=https://webpath.med.utah.edu/LIVEHTML/LIVER019.html\|title=The Internet Pathology Laboratory for Medical Education\|website=The University of Utah Eccles Health Sciences Library\|accessdate=2020-12-18}}</ref>
	</gallery>		</gallery>

Mikael Häggström: /* Gross processing in autopsy */ Templated

2022-06-20T01:54:53Z

Gross processing in autopsy: Templated

← Older revision		Revision as of 21:54, 19 June 2022
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	</gallery>		</gallery>
	*Look for any '''focal change''' in the liver volume, mainly any tumor. If found: {{Further\|Liver tumor\|linebreak=no}}		*Look for any '''focal change''' in the liver volume, mainly any tumor. If found: {{Further\|Liver tumor\|linebreak=no}}
	*Determine liver '''weight'''. The standard reference range for men is 970–1,860 g (2.14–4.10 lb)<ref name="MolinaDiMaio2012">{{cite journal\|last1=Molina\|first1=D. Kimberley\|last2=DiMaio\|first2=Vincent J.M.\|title=Normal Organ Weights in Men\|journal=The American Journal of Forensic Medicine and Pathology\|volume=33\|issue=4\|year=2012\|pages=368–372\|issn=0195-7910\|doi=10.1097/PAF.0b013e31823d29ad\|pmid=22182984\|s2cid=32174574}}</ref> and for women 600–1,770 g (1.32–3.90 lb).<ref name="MolinaDiMaio2015">{{cite journal\|last1=Molina\|first1=D. Kimberley\|last2=DiMaio\|first2=Vincent J. M.\|title=Normal Organ Weights in Women\|journal=The American Journal of Forensic Medicine and Pathology\|volume=36\|issue=3\|year=2015\|pages=182–187\|issn=0195-7910\|doi=10.1097/PAF.0000000000000175\|pmid=26108038\|s2cid=25319215}}</ref>		*Determine liver '''weight'''. The standard reference range for men is 970–1,860 g (2.14–4.10 lb)<ref name="MolinaDiMaio2012">{{MolinaDiMaio2012}}</ref> and for women 600–1,770 g (1.32–3.90 lb).<ref name="MolinaDiMaio2015">{{MolinaDiMaio2015}}</ref>
	*Make consecutive liver slices, such as in the sagittal or coronal plane.		*Make consecutive liver slices, such as in the sagittal or coronal plane.

Mikael Häggström: Cleanup

2021-12-08T20:02:24Z

Cleanup

← Older revision		Revision as of 16:02, 8 December 2021
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	==Gross processing in autopsy==		==Gross processing in autopsy==
	~~Make consecutive liver slices, such as in the sagittal or coronal plane.~~

	~~===Basic gross examination===~~
	*{{Comprehensive-begin}}Measure the distance from the liver edge to the right costal margin.{{Comprehensive-end}}		*{{Comprehensive-begin}}Measure the distance from the liver edge to the right costal margin.{{Comprehensive-end}}
	*'''Inspect''' the color and texture of the surfaces, including external and cut surfaces. Potential pathologies:		*'''Inspect''' the color and texture of the surfaces, including external and cut surfaces. Potential pathologies:
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	*Look for any '''focal change''' in the liver volume, mainly any tumor. If found: {{Further\|Liver tumor\|linebreak=no}}		*Look for any '''focal change''' in the liver volume, mainly any tumor. If found: {{Further\|Liver tumor\|linebreak=no}}
	*Determine liver '''weight'''. The standard reference range for men is 970–1,860 g (2.14–4.10 lb)<ref name="MolinaDiMaio2012">{{cite journal\|last1=Molina\|first1=D. Kimberley\|last2=DiMaio\|first2=Vincent J.M.\|title=Normal Organ Weights in Men\|journal=The American Journal of Forensic Medicine and Pathology\|volume=33\|issue=4\|year=2012\|pages=368–372\|issn=0195-7910\|doi=10.1097/PAF.0b013e31823d29ad\|pmid=22182984\|s2cid=32174574}}</ref> and for women 600–1,770 g (1.32–3.90 lb).<ref name="MolinaDiMaio2015">{{cite journal\|last1=Molina\|first1=D. Kimberley\|last2=DiMaio\|first2=Vincent J. M.\|title=Normal Organ Weights in Women\|journal=The American Journal of Forensic Medicine and Pathology\|volume=36\|issue=3\|year=2015\|pages=182–187\|issn=0195-7910\|doi=10.1097/PAF.0000000000000175\|pmid=26108038\|s2cid=25319215}}</ref>		*Determine liver '''weight'''. The standard reference range for men is 970–1,860 g (2.14–4.10 lb)<ref name="MolinaDiMaio2012">{{cite journal\|last1=Molina\|first1=D. Kimberley\|last2=DiMaio\|first2=Vincent J.M.\|title=Normal Organ Weights in Men\|journal=The American Journal of Forensic Medicine and Pathology\|volume=33\|issue=4\|year=2012\|pages=368–372\|issn=0195-7910\|doi=10.1097/PAF.0b013e31823d29ad\|pmid=22182984\|s2cid=32174574}}</ref> and for women 600–1,770 g (1.32–3.90 lb).<ref name="MolinaDiMaio2015">{{cite journal\|last1=Molina\|first1=D. Kimberley\|last2=DiMaio\|first2=Vincent J. M.\|title=Normal Organ Weights in Women\|journal=The American Journal of Forensic Medicine and Pathology\|volume=36\|issue=3\|year=2015\|pages=182–187\|issn=0195-7910\|doi=10.1097/PAF.0000000000000175\|pmid=26108038\|s2cid=25319215}}</ref>
			*Make consecutive liver slices, such as in the sagittal or coronal plane.

	===Gross report===		===Gross report in autopsy===
	*{{Comprehensive-begin}}Distance from the liver edge to the right costal margin.{{Comprehensive-end}}		*{{Comprehensive-begin}}Distance from the liver edge to the right costal margin.{{Comprehensive-end}}
	*'''Weight'''. If abnormally low or high, preferably include the reference range.		*'''Weight'''. If abnormally low or high, preferably include the reference range.
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	{{Autopsy report of liver}}		{{Autopsy report of liver}}

	==Microscopic evaluation ~~in autopsy~~==		==Microscopic evaluation==
	[[File:Histopathology of liver zones.jpg\|thumb\|Pathologies can be topographically classified by liver zones. P: portal tract. V: central vein.]]		[[File:Histopathology of liver zones.jpg\|thumb\|Pathologies can be topographically classified by liver zones. P: portal tract. V: central vein.]]
	A ~~minimal~~ screening ~~of autopsy specimens include~~:		A general screening includes:
	*A severity grading of '''previously known liver diseases'''.		*A severity grading of '''previously known liver diseases'''.
	:*Commonly, this includes to quantify any '''cirrhosis''', at least if the patient had alcohol abuse.		:*Commonly, this includes to quantify any '''cirrhosis''', at least if the patient had alcohol abuse.
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	</gallery>		</gallery>

	===~~Acute liver failure===~~		===Signs of acute liver failure===
	~~Acute liver failure has multiple etiologies, and hence various presentations. Regardless~~ of ~~etiology, the initial hepatic insult that leads to~~ acute liver failure is “hepatitis” in the broadest sense, with extensive hepatocyte injury and necrosis. The initiating process may damage the liver by zonal necrosis (with a centrilobular or acinar zones 3 necrosis indicating mainly acetaminophen hepatotoxicity), or it may damage the liver by a diffuse hepatitis with necrosis and inflammation as exemplified by acute viral hepatitis A, B, or E infections or other drug hepatotoxicities.<ref name="Lefkowitch2016">{{cite journal\|last1=Lefkowitch\|first1=Jay H.\|title=The Pathology of Acute Liver Failure\|journal=Advances In Anatomic Pathology\|volume=23\|issue=3\|year=2016\|pages=~~144–158\|issn~~=~~1072-4109\|doi~~=~~10.1097/PAP.0000000000000112}}</ref>~~
	<gallery mode=packed heights=200>>		<gallery mode=packed heights=200>>
	File:Histopathology of acute hepatitis.jpg\|~~Histopathology of '''acute hepatitis''' with lobular~~ disarray and associated lymphocytic inflammation, acidophil acidophil body formation (arrow) and bilirubinostasis.<ref name="BoydCain2020"/>		File:Histopathology of acute hepatitis.jpg\|Lobular disarray and associated lymphocytic inflammation, acidophil acidophil body formation (arrow) and bilirubinostasis, suggesting '''acute hepatitis'''.<ref name="BoydCain2020"/>
	File:Histopathology of shock liver (intermediate magnification), annotated.jpg\|'''Shock liver''', showing its hallmark<ref name="pmid29868133">{{cite journal\| author=Ciobanu AO, Gherasim L\| title=Ischemic Hepatitis - Intercorrelated Pathology. \| journal=Maedica (Bucur) \| year= 2018 \| volume= 13 \| issue= 1 \| pages= 5-11 \| pmid=29868133 \| doi= \| pmc=5972787 \| url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29868133 }}</ref> pathologic finding centrilobular necrosis but viable periportal hepatocytes. The necrotic hepatocytes are seen as slightly more eosinophilic (red) and discohesive.		File:Histopathology of shock liver (intermediate magnification), annotated.jpg\|'''Shock liver''', showing its hallmark<ref name="pmid29868133">{{cite journal\| author=Ciobanu AO, Gherasim L\| title=Ischemic Hepatitis - Intercorrelated Pathology. \| journal=Maedica (Bucur) \| year= 2018 \| volume= 13 \| issue= 1 \| pages= 5-11 \| pmid=29868133 \| doi= \| pmc=5972787 \| url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29868133 }}</ref> pathologic finding centrilobular necrosis but viable periportal hepatocytes. The necrotic hepatocytes are seen as slightly more eosinophilic (red) and discohesive.
	File:Histopathology of massive hepatic necrosis in hepatitis B.jpg\|'''Massive hepatic necrosis''': Liver cell dropout, residual hepatocytes and intact portal tract pattern.<ref>{{cite journal\|last1=Xue\|first1=Ran\|last2=Zhu\|first2=Yueke\|last3=Liu\|first3=Hui\|last4=Meng\|first4=Qinghua\|title=The clinical parameters for the diagnosis of hepatitis B virus related acute-on-chronic liver failure with sepsis\|journal=Scientific Reports\|volume=9\|issue=1\|year=2019\|issn=2045-2322\|doi=10.1038/s41598-019-38866-3}}<br>-"This article is licensed under a Creative Commons Attribution 4.0 International License"</ref>		File:Histopathology of massive hepatic necrosis in hepatitis B.jpg\|'''Massive hepatic necrosis''': Liver cell dropout, residual hepatocytes and intact portal tract pattern.<ref>{{cite journal\|last1=Xue\|first1=Ran\|last2=Zhu\|first2=Yueke\|last3=Liu\|first3=Hui\|last4=Meng\|first4=Qinghua\|title=The clinical parameters for the diagnosis of hepatitis B virus related acute-on-chronic liver failure with sepsis\|journal=Scientific Reports\|volume=9\|issue=1\|year=2019\|issn=2045-2322\|doi=10.1038/s41598-019-38866-3}}<br>-"This article is licensed under a Creative Commons Attribution 4.0 International License"</ref>
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	*At least if the patient had alcohol abuse, a quantification of cirrhosis.		*At least if the patient had alcohol abuse, a quantification of cirrhosis.
	*Optionally, even absence of hepatitis, malignancy, congestive hepatopathy and/or steatosis.		*Optionally, even absence of hepatitis, malignancy, congestive hepatopathy and/or steatosis.

	~~==Microscopic examination in excisions==~~
	~~Mainly look for tumors. {{further\|Liver tumor}}~~

	{{Bottom}}		{{Bottom}}

Mikael Häggström: /* Gross report */ Example

2021-12-08T19:54:57Z

Gross report: Example

← Older revision		Revision as of 15:54, 8 December 2021
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	*'''Color and texture''' of cut surfaces		*'''Color and texture''' of cut surfaces
	*Any '''focal change'''		*Any '''focal change'''
	{{~~For\|an example\|~~Autopsy}}		Example:
			{{Autopsy report of liver}}

	==Microscopic evaluation in autopsy==		==Microscopic evaluation in autopsy==

Mikael Häggström: /* Gross processing in autopsy */ +Example

2021-12-08T19:50:29Z

Gross processing in autopsy: +Example

← Older revision		Revision as of 15:50, 8 December 2021
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	===Basic gross examination===		===Basic gross examination===
			*{{Comprehensive-begin}}Measure the distance from the liver edge to the right costal margin.{{Comprehensive-end}}
	*'''Inspect''' the color and texture of the surfaces, including external and cut surfaces. Potential pathologies:		*'''Inspect''' the color and texture of the surfaces, including external and cut surfaces. Potential pathologies:
	<gallery mode=packed heights=190>		<gallery mode=packed heights=190>
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	===Gross report===		===Gross report===
			*{{Comprehensive-begin}}Distance from the liver edge to the right costal margin.{{Comprehensive-end}}
	*'''Weight'''. If abnormally low or high, preferably include the reference range.		*'''Weight'''. If abnormally low or high, preferably include the reference range.
	*'''Color and texture''' of cut surfaces		*'''Color and texture''' of cut surfaces
	*Any '''focal change'''		*Any '''focal change'''
			{{For\|an example\|Autopsy}}

	==Microscopic evaluation in autopsy==		==Microscopic evaluation in autopsy==