Template:Hepatocellular adenoma versus carcinoma - Revision history

Mikael Häggström: /* Hepatocellular adenoma versus carcinoma */ adenoma

2021-02-11T14:53:22Z

Hepatocellular adenoma versus carcinoma: adenoma

← Older revision		Revision as of 10:53, 11 February 2021
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	===Hepatocellular adenoma versus carcinoma===		===Hepatocellular adenoma versus carcinoma===
	[[File:Histopathology of inflammatory hepatocellular adenoma.jpg\|thumb\|Histopathology of inflammatory hepatocellular adenoma, with inflammatory cells and minor atypia.<ref name="Bioulac-SageSempoux2013">{{cite journal\|last1=Bioulac-Sage\|first1=Paulette\|last2=Sempoux\|first2=Christine\|last3=Possenti\|first3=Laurent\|last4=Frulio\|first4=Nora\|last5=Laumonier\|first5=Hervé\|last6=Laurent\|first6=Christophe\|last7=Chiche\|first7=Laurence\|last8=Frédéric Blanc\|first8=Jean\|last9=Saric\|first9=Jean\|last10=Trillaud\|first10=Hervé\|last11=Le Bail\|first11=Brigitte\|last12=Balabaud\|first12=Charles\|title=Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context\|journal=International Journal of Hepatology\|volume=2013\|year=2013\|pages=1–13\|issn=2090-3448\|doi=10.1155/2013/253261}}</ref>]]		[[File:Histopathology of inflammatory hepatocellular adenoma.jpg\|thumb\|Histopathology of inflammatory hepatocellular '''adenoma''', with inflammatory cells and minor atypia.<ref name="Bioulac-SageSempoux2013">{{cite journal\|last1=Bioulac-Sage\|first1=Paulette\|last2=Sempoux\|first2=Christine\|last3=Possenti\|first3=Laurent\|last4=Frulio\|first4=Nora\|last5=Laumonier\|first5=Hervé\|last6=Laurent\|first6=Christophe\|last7=Chiche\|first7=Laurence\|last8=Frédéric Blanc\|first8=Jean\|last9=Saric\|first9=Jean\|last10=Trillaud\|first10=Hervé\|last11=Le Bail\|first11=Brigitte\|last12=Balabaud\|first12=Charles\|title=Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context\|journal=International Journal of Hepatology\|volume=2013\|year=2013\|pages=1–13\|issn=2090-3448\|doi=10.1155/2013/253261}}</ref>]]
	A '''hepatocellular adenoma''', in contrast to a carcinoma, has a well-defined border between the lesion and background liver, and is composed of hepatocytes with less significant cytologic atypia.<ref>{{cite web\|url=https://www.pathologyoutlines.com/topic/livertumorhepatocellularadenoma.html\|title=Liver & intrahepatic bile ducts - Benign / nonneoplastic - Hepatocellular adenoma\|author=Author: Avani Pendse, M.D., Ph.D.\|website=Pathology Outlines}} Topic Completed: 1 October 2018. Minor changes: 30 September 2020</ref>		A '''hepatocellular adenoma''', in contrast to a carcinoma, has a well-defined border between the lesion and background liver, and is composed of hepatocytes with less significant cytologic atypia.<ref>{{cite web\|url=https://www.pathologyoutlines.com/topic/livertumorhepatocellularadenoma.html\|title=Liver & intrahepatic bile ducts - Benign / nonneoplastic - Hepatocellular adenoma\|author=Author: Avani Pendse, M.D., Ph.D.\|website=Pathology Outlines}} Topic Completed: 1 October 2018. Minor changes: 30 September 2020</ref>

Mikael Häggström: Emphasized

2021-02-11T14:49:55Z

Emphasized

← Older revision		Revision as of 10:49, 11 February 2021
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	===Hepatocellular adenoma versus carcinoma===		===Hepatocellular adenoma versus carcinoma===
	[[File:Histopathology of inflammatory hepatocellular adenoma.jpg\|thumb\|Histopathology of inflammatory hepatocellular adenoma, with inflammatory cells and minor atypia.<ref name="Bioulac-SageSempoux2013">{{cite journal\|last1=Bioulac-Sage\|first1=Paulette\|last2=Sempoux\|first2=Christine\|last3=Possenti\|first3=Laurent\|last4=Frulio\|first4=Nora\|last5=Laumonier\|first5=Hervé\|last6=Laurent\|first6=Christophe\|last7=Chiche\|first7=Laurence\|last8=Frédéric Blanc\|first8=Jean\|last9=Saric\|first9=Jean\|last10=Trillaud\|first10=Hervé\|last11=Le Bail\|first11=Brigitte\|last12=Balabaud\|first12=Charles\|title=Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context\|journal=International Journal of Hepatology\|volume=2013\|year=2013\|pages=1–13\|issn=2090-3448\|doi=10.1155/2013/253261}}</ref>]]		[[File:Histopathology of inflammatory hepatocellular adenoma.jpg\|thumb\|Histopathology of inflammatory hepatocellular adenoma, with inflammatory cells and minor atypia.<ref name="Bioulac-SageSempoux2013">{{cite journal\|last1=Bioulac-Sage\|first1=Paulette\|last2=Sempoux\|first2=Christine\|last3=Possenti\|first3=Laurent\|last4=Frulio\|first4=Nora\|last5=Laumonier\|first5=Hervé\|last6=Laurent\|first6=Christophe\|last7=Chiche\|first7=Laurence\|last8=Frédéric Blanc\|first8=Jean\|last9=Saric\|first9=Jean\|last10=Trillaud\|first10=Hervé\|last11=Le Bail\|first11=Brigitte\|last12=Balabaud\|first12=Charles\|title=Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context\|journal=International Journal of Hepatology\|volume=2013\|year=2013\|pages=1–13\|issn=2090-3448\|doi=10.1155/2013/253261}}</ref>]]
	A '''hepatocellular adenoma''', in contrast, has a well-defined border between the lesion and background liver, and is composed of hepatocytes with less significant cytologic atypia.<ref>{{cite web\|url=https://www.pathologyoutlines.com/topic/livertumorhepatocellularadenoma.html\|title=Liver & intrahepatic bile ducts - Benign / nonneoplastic - Hepatocellular adenoma\|author=Author: Avani Pendse, M.D., Ph.D.\|website=Pathology Outlines}} Topic Completed: 1 October 2018. Minor changes: 30 September 2020</ref>		A '''hepatocellular adenoma''', in contrast to a carcinoma, has a well-defined border between the lesion and background liver, and is composed of hepatocytes with less significant cytologic atypia.<ref>{{cite web\|url=https://www.pathologyoutlines.com/topic/livertumorhepatocellularadenoma.html\|title=Liver & intrahepatic bile ducts - Benign / nonneoplastic - Hepatocellular adenoma\|author=Author: Avani Pendse, M.D., Ph.D.\|website=Pathology Outlines}} Topic Completed: 1 October 2018. Minor changes: 30 September 2020</ref>

	Both hepatocellular adenoma and well-differentiated hepatocellular carcinoma may display:		Both hepatocellular adenoma and well-differentiated hepatocellular carcinoma may display:
	*'''Steatosis''': A steatotic hepatocellular carcinoma is a common variant, found most commonly in small, well-differentiated tumors.<ref name="ChanYu2016">{{cite journal\|last1=Chan\|first1=Anthony W H\|last2=Yu\|first2=Shuangni\|last3=Yu\|first3=Yau-Hei\|last4=Tong\|first4=Joanna H M\|last5=Wang\|first5=Lei\|last6=Tin\|first6=Edith K Y\|last7=Chong\|first7=Charing C N\|last8=Chan\|first8=Stephen L\|last9=Wong\|first9=Grace L H\|last10=Wong\|first10=Vincent W S\|last11=Chan\|first11=Henry L Y\|last12=Lai\|first12=Paul B S\|last13=To\|first13=Ka-Fai\|title=Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse\|journal=Histopathology\|volume=69\|issue=6\|year=2016\|pages=971–984\|issn=03090167\|doi=10.1111/his.13029}}</ref>		*'''Steatosis''': A steatotic hepatocellular carcinoma is a common variant, found most commonly in small, well-differentiated tumors.<ref name="ChanYu2016">{{cite journal\|last1=Chan\|first1=Anthony W H\|last2=Yu\|first2=Shuangni\|last3=Yu\|first3=Yau-Hei\|last4=Tong\|first4=Joanna H M\|last5=Wang\|first5=Lei\|last6=Tin\|first6=Edith K Y\|last7=Chong\|first7=Charing C N\|last8=Chan\|first8=Stephen L\|last9=Wong\|first9=Grace L H\|last10=Wong\|first10=Vincent W S\|last11=Chan\|first11=Henry L Y\|last12=Lai\|first12=Paul B S\|last13=To\|first13=Ka-Fai\|title=Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse\|journal=Histopathology\|volume=69\|issue=6\|year=2016\|pages=971–984\|issn=03090167\|doi=10.1111/his.13029}}</ref>
	*'''Portal triads''', which commonly persist in well-differentiated hepatocellular carcinomas.<ref name="MotohashiOkudaira1992">{{cite journal\|last1=Motohashi\|first1=Ikuko\|last2=Okudaira\|first2=Masahiko\|last3=Takai\|first3=Tomoko\|last4=Kaneko\|first4=Satoshi\|last5=Ikeda\|first5=Noriaki\|title=Morphological differences between hepatocellular carcinoma and hepatocellular carcinomalike lesions\|journal=Hepatology\|volume=16\|issue=1\|year=1992\|pages=118–126\|issn=02709139\|doi=10.1002/hep.1840160120}}</ref>		*'''Portal triads''', which commonly persist in well-differentiated hepatocellular carcinomas.<ref name="MotohashiOkudaira1992">{{cite journal\|last1=Motohashi\|first1=Ikuko\|last2=Okudaira\|first2=Masahiko\|last3=Takai\|first3=Tomoko\|last4=Kaneko\|first4=Satoshi\|last5=Ikeda\|first5=Noriaki\|title=Morphological differences between hepatocellular carcinoma and hepatocellular carcinomalike lesions\|journal=Hepatology\|volume=16\|issue=1\|year=1992\|pages=118–126\|issn=02709139\|doi=10.1002/hep.1840160120}}</ref>

Mikael Häggström: Templated

2021-02-11T14:49:08Z

Templated

New page

===Hepatocellular adenoma versus carcinoma===
[[File:Histopathology of inflammatory hepatocellular adenoma.jpg|thumb|Histopathology of inflammatory hepatocellular adenoma, with inflammatory cells and minor atypia.<ref name="Bioulac-SageSempoux2013">{{cite journal|last1=Bioulac-Sage|first1=Paulette|last2=Sempoux|first2=Christine|last3=Possenti|first3=Laurent|last4=Frulio|first4=Nora|last5=Laumonier|first5=Hervé|last6=Laurent|first6=Christophe|last7=Chiche|first7=Laurence|last8=Frédéric Blanc|first8=Jean|last9=Saric|first9=Jean|last10=Trillaud|first10=Hervé|last11=Le Bail|first11=Brigitte|last12=Balabaud|first12=Charles|title=Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context|journal=International Journal of Hepatology|volume=2013|year=2013|pages=1–13|issn=2090-3448|doi=10.1155/2013/253261}}</ref>]]
A '''hepatocellular adenoma''', in contrast, has a well-defined border between the lesion and background liver, and is composed of hepatocytes with less significant cytologic atypia.<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/livertumorhepatocellularadenoma.html|title=Liver & intrahepatic bile ducts - Benign / nonneoplastic - Hepatocellular adenoma|author=Author: Avani Pendse, M.D., Ph.D.|website=Pathology Outlines}} Topic Completed: 1 October 2018. Minor changes: 30 September 2020</ref>

Both hepatocellular adenoma and well-differentiated hepatocellular carcinoma may display:
*'''Steatosis''': A steatotic hepatocellular carcinoma is a common variant, found most commonly in small, well-differentiated tumors.<ref name="ChanYu2016">{{cite journal|last1=Chan|first1=Anthony W H|last2=Yu|first2=Shuangni|last3=Yu|first3=Yau-Hei|last4=Tong|first4=Joanna H M|last5=Wang|first5=Lei|last6=Tin|first6=Edith K Y|last7=Chong|first7=Charing C N|last8=Chan|first8=Stephen L|last9=Wong|first9=Grace L H|last10=Wong|first10=Vincent W S|last11=Chan|first11=Henry L Y|last12=Lai|first12=Paul B S|last13=To|first13=Ka-Fai|title=Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse|journal=Histopathology|volume=69|issue=6|year=2016|pages=971–984|issn=03090167|doi=10.1111/his.13029}}</ref>
*'''Portal triads''', which commonly persist in well-differentiated hepatocellular carcinomas.<ref name="MotohashiOkudaira1992">{{cite journal|last1=Motohashi|first1=Ikuko|last2=Okudaira|first2=Masahiko|last3=Takai|first3=Tomoko|last4=Kaneko|first4=Satoshi|last5=Ikeda|first5=Noriaki|title=Morphological differences between hepatocellular carcinoma and hepatocellular carcinomalike lesions|journal=Hepatology|volume=16|issue=1|year=1992|pages=118–126|issn=02709139|doi=10.1002/hep.1840160120}}</ref>