Hepatocellular carcinoma: Difference between revisions
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→Microscopic evaluation: +Adenoma |
→Differentiation: Reporting |
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===Differentiation=== | ===Differentiation=== | ||
Differentiations of hepatocellular carcinoma are:<ref name=Deepali/> | Differentiations of hepatocellular carcinoma are:<ref name=Deepali/> | ||
*'''Well differentiated''': | *'''Well differentiated''': | ||
:*Thin plates (1 - 3 hepatocytes thick) | :*Thin plates (1 - 3 hepatocytes thick) | ||
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:*Minimal nuclear atypia | :*Minimal nuclear atypia | ||
:*Nuclear density of 2x compared to normal liver | :*Nuclear density of 2x compared to normal liver | ||
*'''Moderately differentiated''': | *'''Moderately differentiated''': | ||
:*Trabecular pattern at least 4 cells thick | :*Trabecular pattern at least 4 cells thick | ||
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:*Distinct nucleoli | :*Distinct nucleoli | ||
:*Pseudoglands | :*Pseudoglands | ||
*'''Poorly differentiated''': | *'''Poorly differentiated''': | ||
:*Large tumor cells with hyperchromatic nuclei in compact growth pattern | :*Large tumor cells with hyperchromatic nuclei in compact growth pattern | ||
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:*Prominent pleomorphism | :*Prominent pleomorphism | ||
:*May have spindle cell or small cell areas | :*May have spindle cell or small cell areas | ||
<gallery mode=packed heights=190> | |||
File:Histopathology of well-differentiated hepatocellular carcinoma.jpg|Well-differentiated HCC. | |||
File:Histopathology of moderately differentiated hepatocellular carcinoma.jpg|Moderately differentiated HCC. | |||
File:Histopathology of poorly differentiated hepatocellular carcinoma.jpg|Poorly differentiated HCC. | |||
</gallery> | |||
==Reporting== | |||
{{CAP}} | |||
{{Reporting}} | |||
{{Bottom}} | {{Bottom}} | ||