Template:Brain - autopsy gross processing: Difference between revisions
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*'''Weight''' the brain. Overall normal range (95% prediction interval) is 1100 to 1700 g,<ref name="GovenderLazarus2018">{{cite journal|last1=Govender|first1=S|last2=Lazarus|first2=L|last3=De-Gama|first3=B. Z|last4=Satyapal|first4=K. S|title=Post-Mortem Brain Weight Reference Range for a Select South African Population|journal=International Journal of Morphology|volume=36|issue=3|year=2018|pages=915–920|issn=0717-9502|doi=10.4067/S0717-95022018000300915}}</ref> +60g for males and -60g for females.<ref>{{Cite book|url = https://books.google.com/books?id=u1bwQj7qdsYC|title = Reader in Gender archaeology|access-date = 2014-09-21|publisher = Routlegde|author1=Kelley Hays |author2=David S. |isbn = 9780415173605|year = 1998}}</ref> | |||
*'''Inspect''': Grooves indicating herniation? Hemorrhages? | *'''Inspect''': Grooves indicating herniation? Hemorrhages? | ||
*Dissect the '''basilar artery''' and '''circle of Willis''', either before or after separation from the brain. | *Dissect the '''basilar artery''' and '''circle of Willis''', either before or after separation from the brain. {{Comment-begin}}If there is likely a need to demonstrate the case to an additional person later, the arteries of the skull base are preferably dissected after first separating them from the brain.{{Comment-end}} Look mainly for thromboses. | ||
*Separate the '''brainstem''', '''cerebellum''' and '''cerebrum''', which may be done by first separating the former two together from the cerebrum. | *Separate the '''brainstem''', '''cerebellum''' and '''cerebrum''', which may be done by first separating the former two together from the cerebrum. | ||
[[File:Alzheimer's disease brain comparison.jpg|thumb|450px|Normal brain versus in Alzheimer's disease.]] | [[File:Alzheimer's disease brain comparison.jpg|thumb|450px|Normal brain versus in Alzheimer's disease.]] | ||
*Slice each part, looking for hemorrhages and/or infarcts. At least in people aged over 65-75 years of age {{Finding-begin}}or with suggestive history{{Finding-end}}, look for signs of Alzhemier's disease (see picture). | *'''Slice''' each part, looking for hemorrhages and/or infarcts. | ||
:*For the cerebrum, cut it into slices about 1 cm thick. It can be done from frontal to occipital, or by starting coronally into two halves at the level of the mammillary bodies and continuing in each direction from there. | |||
*At least in people aged over 65-75 years of age {{Finding-begin}}or with suggestive history{{Finding-end}}, look for signs of Alzhemier's disease (see picture). | |||
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Latest revision as of 14:24, 21 June 2022
Author:
Mikael Häggström [note 1]
- Weight the brain. Overall normal range (95% prediction interval) is 1100 to 1700 g,[1] +60g for males and -60g for females.[2]
- Inspect: Grooves indicating herniation? Hemorrhages?
- Dissect the basilar artery and circle of Willis, either before or after separation from the brain. [[If there is likely a need to demonstrate the case to an additional person later, the arteries of the skull base are preferably dissected after first separating them from the brain.]] Look mainly for thromboses.
- Separate the brainstem, cerebellum and cerebrum, which may be done by first separating the former two together from the cerebrum.
- Slice each part, looking for hemorrhages and/or infarcts.
- For the cerebrum, cut it into slices about 1 cm thick. It can be done from frontal to occipital, or by starting coronally into two halves at the level of the mammillary bodies and continuing in each direction from there.
- At least in people aged over 65-75 years of age {{or with suggestive history}}, look for signs of Alzhemier's disease (see picture).
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Govender, S; Lazarus, L; De-Gama, B. Z; Satyapal, K. S (2018). "Post-Mortem Brain Weight Reference Range for a Select South African Population ". International Journal of Morphology 36 (3): 915–920. doi:. ISSN 0717-9502.
- ↑ Kelley Hays; David S. (1998). Reader in Gender archaeology . Routlegde. ISBN 9780415173605. Retrieved on 2014-09-21.
Image sources