Salivary glands: Difference between revisions
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File:Cytopathology of Warthin's tumor.jpg|'''Warthin's tumor''', with typical cellular features (and relatively uncommon binucleated cells).<ref>Image by Mikael Häggström, MD. References for entries:<br>- {{cite journal| author=Köybaşioğlu FF, Önal B, Han Ü, Adabağ A, Şahpaz A| title=Cytomorphological findings in diagnosis of Warthin tumor | journal=Turk J Med Sci | year= 2020 | volume= 50 | issue= 1 | pages= 148-154 | pmid=31769640 | doi=10.3906/sag-1901-215 | pmc=7080357 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31769640}}<br>Binucleation:<br>- {{cite web|url=http://repository-tnmgrmu.ac.in/464/1/200300307malliga.pdf|title=A correlative cytological and histopathological study on lesions of salivary gland|date=2006-10-18|author=Dr.S. Malliga}}<br>- Chan MKM, McGuire LJ: Cytodiagnosis of Lesions Presenting as Salivary Gland Swellings: A Report of Seven Cases. Diagn Cytopathol 8: 439-443, 1992b.</ref> Pap stain. For a diagnosis, you should see sheets of oncocytes and a mixed population of lymphocytes.<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/salivaryglandswarthin.html|title=Warthin tumor|website=Pathology Outlines|author=Adriana Handra-Luca, M.D., Ph.D., Jen-Fan Hang, M.D.}} Last author update: 1 September 2012. Last staff update: 28 June 2022</ref> | File:Cytopathology of Warthin's tumor.jpg|'''Warthin's tumor''', with typical cellular features (and relatively uncommon binucleated cells).<ref>Image by Mikael Häggström, MD. References for entries:<br>- {{cite journal| author=Köybaşioğlu FF, Önal B, Han Ü, Adabağ A, Şahpaz A| title=Cytomorphological findings in diagnosis of Warthin tumor | journal=Turk J Med Sci | year= 2020 | volume= 50 | issue= 1 | pages= 148-154 | pmid=31769640 | doi=10.3906/sag-1901-215 | pmc=7080357 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31769640}}<br>Binucleation:<br>- {{cite web|url=http://repository-tnmgrmu.ac.in/464/1/200300307malliga.pdf|title=A correlative cytological and histopathological study on lesions of salivary gland|date=2006-10-18|author=Dr.S. Malliga}}<br>- Chan MKM, McGuire LJ: Cytodiagnosis of Lesions Presenting as Salivary Gland Swellings: A Report of Seven Cases. Diagn Cytopathol 8: 439-443, 1992b.</ref> Pap stain. For a diagnosis, you should see sheets of oncocytes and a mixed population of lymphocytes.<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/salivaryglandswarthin.html|title=Warthin tumor|website=Pathology Outlines|author=Adriana Handra-Luca, M.D., Ph.D., Jen-Fan Hang, M.D.}} Last author update: 1 September 2012. Last staff update: 28 June 2022</ref> | ||
</gallery> | </gallery> | ||
==Reporting=== | |||
Example report: | |||
{|class=wikitable | |||
|Right parotid mass, biopsy:<br>– Pleomorphic adenoma. | |||
|} | |||
{{Bottom}} | {{Bottom}} | ||
Latest revision as of 12:08, 13 November 2023
Author:
Mikael Häggström, M.D. [note 1]
The major salivary glands are the parotid, submandibular, and sublingual glands.
Evaluation
Look for the most common tumors:
-
![Relative incidence of parotid tumors.[1]](https://upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Relative_incidence_of_parotid_tumors.png/960px-Relative_incidence_of_parotid_tumors.png)
Relative incidence of parotid tumors.[1] -
![Relative incidence of submandibular tumors.[1]](https://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Relative_incidence_of_submandibular_tumors.png/960px-Relative_incidence_of_submandibular_tumors.png)
Relative incidence of submandibular tumors.[1] -
![Pleomorphic adenoma (also called benign mixed tumor), H&E stain.[2]](https://upload.wikimedia.org/wikipedia/commons/thumb/8/8a/Histopathology_of_pleomorphic_adenoma.png/500px-Histopathology_of_pleomorphic_adenoma.png)
Pleomorphic adenoma (also called benign mixed tumor), H&E stain.[2]
![Relative incidence of parotid tumors.[1]](/File:Relative_incidence_of_parotid_tumors.png)
![Relative incidence of submandibular tumors.[1]](/File:Relative_incidence_of_submandibular_tumors.png)
![Pleomorphic adenoma (also called benign mixed tumor), H&E stain.[2]](/File:Histopathology_of_pleomorphic_adenoma.png)
Cytology
-
![Pleomorphic adenoma (Pap stain). It can usually be diagnosed by its typical fibrillary stroma (mesenchyme). Stromal cell nuclei are small. Myoepithelial cells are usually the predominant cell type, and can have various shapes but are usually more elongated than epithelial cells. Epithelial cells may have prominent nucleoli.[3]](https://upload.wikimedia.org/wikipedia/commons/thumb/8/83/Cytopathology_of_pleomorphic_adenoma.png/500px-Cytopathology_of_pleomorphic_adenoma.png)
Pleomorphic adenoma (Pap stain). It can usually be diagnosed by its typical fibrillary stroma (mesenchyme). Stromal cell nuclei are small. Myoepithelial cells are usually the predominant cell type, and can have various shapes but are usually more elongated than epithelial cells. Epithelial cells may have prominent nucleoli.[3] -
![Warthin's tumor, with typical cellular features (and relatively uncommon binucleated cells).[4] Pap stain. For a diagnosis, you should see sheets of oncocytes and a mixed population of lymphocytes.[5]](https://upload.wikimedia.org/wikipedia/commons/thumb/e/e7/Cytopathology_of_Warthin%27s_tumor.jpg/960px-Cytopathology_of_Warthin%27s_tumor.jpg)
![Pleomorphic adenoma (Pap stain). It can usually be diagnosed by its typical fibrillary stroma (mesenchyme). Stromal cell nuclei are small. Myoepithelial cells are usually the predominant cell type, and can have various shapes but are usually more elongated than epithelial cells. Epithelial cells may have prominent nucleoli.[3]](/File:Cytopathology_of_pleomorphic_adenoma.png)
![Warthin's tumor, with typical cellular features (and relatively uncommon binucleated cells).[4] Pap stain. For a diagnosis, you should see sheets of oncocytes and a mixed population of lymphocytes.[5]](/File:Cytopathology_of_Warthin%27s_tumor.jpg)
Reporting=
Example report:
| Right parotid mass, biopsy: – Pleomorphic adenoma. |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Steve C Lee, MD, PhD. Salivary Gland Neoplasms. Medscape. Updated: Jan 13, 2021}}
Diagrams by Mikael Häggström, MD - ↑ Image by Mikael Häggström, MD. Reference for description: Bin Xu, M.D., Ph.D.. Pleomorphic adenoma. Pathology Outlines. Last author update: 30 July 2021. Last staff update: 6 February 2023
- ↑ Image by Mikael Häggström, MD. Reference for description: Bin Xu, M.D., Ph.D.. Pleomorphic adenoma. Last author update: 30 July 2021. Last staff update: 5 August 2021
- ↑ Image by Mikael Häggström, MD. References for entries:
- Köybaşioğlu FF, Önal B, Han Ü, Adabağ A, Şahpaz A (2020). "Cytomorphological findings in diagnosis of Warthin tumor ". Turk J Med Sci 50 (1): 148-154. doi:. PMID 31769640. PMC: 7080357. Archived from the original. .
Binucleation:
- Dr.S. Malliga (2006-10-18). A correlative cytological and histopathological study on lesions of salivary gland.
- Chan MKM, McGuire LJ: Cytodiagnosis of Lesions Presenting as Salivary Gland Swellings: A Report of Seven Cases. Diagn Cytopathol 8: 439-443, 1992b. - ↑ Adriana Handra-Luca, M.D., Ph.D., Jen-Fan Hang, M.D.. Warthin tumor. Pathology Outlines. Last author update: 1 September 2012. Last staff update: 28 June 2022
Image sources