Osteomyelitis: Difference between revisions

Jump to navigation Jump to search
Mikael Häggström (talk | contribs)
Mikael Häggström (talk | contribs)
 
(5 intermediate revisions by the same user not shown)
Line 5: Line 5:


==Gross processing==
==Gross processing==
*Measure the specimen
*'''Measure''' the specimen.
*Put in decalcification, after bisection of visibly affected areas if needed for penetration of the solution
*'''Bisect''' clinically or visibly suspected areas, in longitudinal direction when possible.
*Take sections of visibly afected areas.
*'''Fix''' the specimen in formalin.
*Potentially sample as a standard [[amputation]]
*'''Decalcify''' the specimen.
*'''Sample''' from:
:*Visibly '''affected''' areas
:*Proximal surgical bony '''margin''', if present, [[inked]] and as a longitudinal section.
*Potentially sample as a standard '''[[amputation]]''', such as for '''[[toe]]'''.


==Microscopic evaluation==
==Microscopic evaluation==
Line 17: Line 21:


===Further workup===
===Further workup===
For '''[[toe]]''' amputations, determine its extent, particularly compared to the bony surgical or articular margin. Start at the margin and scan the bone at at least intermediate magnification until inflammation is seen. Preferably make a mark there and measure the distance from the mark to the margin.
[[File:Mark made at significant osteomyelitis inflammation.jpg|thumb|Green mark made at significant osteomyelitis inflammation, by multiple neutrophils.]]
For '''[[toe]]''' amputations, determine its extent, particularly compared to the bony surgical or articular margin. Start at the margin and scan the bone at at least intermediate magnification until significant inflammation is seen. Preferably make a mark there and measure the distance from the mark to the margin.


===Microscopic report===
===Microscopic report===