Lungs: Difference between revisions

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Mikael Häggström (talk | contribs)
Mikael Häggström (talk | contribs)
 
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==Tissue sampling==
==Tissue sampling==
*[[Lung autopsy]]
*[[Lung autopsy]]
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*[[Lung autopsy]]
*[[Lung autopsy]]
*[[Lung wedge resection and lobectomy]]
*[[Lung wedge resection and lobectomy]]
 
*[[Lung biopsy]]
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==Basic microscopic screening==
==Basic microscopic screening==
:''For screening of lung autopsies, see '''[[Lung autopsy]]''' ''
:''For screening of lung autopsies, see '''[[Lung autopsy]]''' ''


Mainly look for '''carcinoma'''. {{further|Lung tumor|linebreak=no}}
Mainly look for '''carcinoma'''. {{further|Lung tumor|linebreak=no}}
If '''granulomas''' are seen, generally stain for acid-fast bacteria and fungi.


===Common findings===
===Common findings===
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File:Histopathology of respiratory epithelial shedding.jpg|Respiratory '''epithelial shedding''' in a small bronchus. If present, look for vascular leakage, mucus hypersecretion and/or widespread airway narrowing, together indicating asthma.<ref>{{cite book | last=Madea | first=B | title=Handbook of forensic medicine | publisher=Wiley-Blackwell | publication-place=Hoboken, N.J | year=2014 | isbn=978-1-118-57062-3 | oclc=872114659 | ref=harv}}</ref>
File:Histopathology of respiratory epithelial shedding.jpg|Respiratory '''epithelial shedding''' in a small bronchus. If present, look for vascular leakage, mucus hypersecretion and/or widespread airway narrowing, together indicating asthma.<ref>{{cite book | last=Madea | first=B | title=Handbook of forensic medicine | publisher=Wiley-Blackwell | publication-place=Hoboken, N.J | year=2014 | isbn=978-1-118-57062-3 | oclc=872114659 | ref=harv}}</ref>
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===Other pertinent findings===
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File:Histopathology of diffuse alveolar damage.jpg|'''hyaline membranes''', suggesting '''diffuse alveolar damage'''.
File:Histopathology of pulmonary aspergillosis.jpg|Pulmonary '''aspergillosis''', seen as acutely branching septated hyphae.<ref>{{cite web|url=https://wellcomecollection.org/works/rsfbcjkv%7Ctitle=Lung: invasive pulmonary aspergillosis with AIDS|website=Wellcome Collection|accessdate=2024-02-21}} License: CC0 1.0 Universal</ref>
File:Histopathology of pulmonary mucormycosis.jpg|Pulmonary '''mucormycosis''', seen as non-septated and broad-branching, and sometimes branching at right angles (black arrow).<ref name="pmid27423701">{{cite journal| author=Lee JH, Hyun JS, Kang DY, Lee HJ, Park SG| title=Rare complication of bronchoesophageal fistula due to pulmonary mucormycosis after induction chemotherapy for acute myeloid leukemia: a case report. | journal=J Med Case Rep | year= 2016 | volume= 10 | issue=  | pages= 195 | pmid=27423701 | doi=10.1186/s13256-016-0991-7 | pmc=4947348 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27423701  }}<br>- "This article is distributed under the terms of the Creative Commons Attribution 4.0 International License"</ref>
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For fungi not conforming to the two main forms above, a general pathologist may attempt to get input by readily available expertise locally, but if it cannot be readily speciated, then it's generally acceptable to simply report as fungi present.
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