Skin: Difference between revisions
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==Fixation== | ==Fixation== | ||
{{Skin fixation, minimal}} | |||
*Suspected '''immunologic disease''':<ref name="ChhabraMinz2012">Page 678 in: {{cite journal|last1=Chhabra|first1=Seema|last2=Minz|first2=RanjanaWalker|last3=Saikia|first3=Biman|title=Immunofluorescence in dermatology|journal=Indian Journal of Dermatology, Venereology, and Leprology|volume=78|issue=6|year=2012|pages=677|issn=0378-6323|doi=10.4103/0378-6323.102355|url=https://pdfs.semanticscholar.org/23d0/148dbe342a93e0bc65a6a2e31040a89113ba.pdf}}</ref> Fixation for immunofluorescence, with for example [[Michel's solution]].<ref name=kvast/> ''For details, see [[immunofluorescense of skin tissues]]'' | *Suspected '''immunologic disease''':<ref name="ChhabraMinz2012">Page 678 in: {{cite journal|last1=Chhabra|first1=Seema|last2=Minz|first2=RanjanaWalker|last3=Saikia|first3=Biman|title=Immunofluorescence in dermatology|journal=Indian Journal of Dermatology, Venereology, and Leprology|volume=78|issue=6|year=2012|pages=677|issn=0378-6323|doi=10.4103/0378-6323.102355|url=https://pdfs.semanticscholar.org/23d0/148dbe342a93e0bc65a6a2e31040a89113ba.pdf}}</ref> Fixation for immunofluorescence, with for example [[Michel's solution]].<ref name=kvast/> ''For details, see [[immunofluorescense of skin tissues]]'' | ||
{{Fixation}} | {{Fixation}} | ||
Revision as of 08:39, 18 September 2019
Author:
Mikael Häggström [note 1]
Fixation
- Generally: Buffered 4% formaldehyde.[1]
- Suspected immunologic disease:[2] Fixation for immunofluorescence, with for example Michel's solution.[1] For details, see immunofluorescense of skin tissues
See also: General notes on fixation
Dark skin focalities
Skin with one or more areas that are darker than the surroundings.
Microscopic evaluation
Evaluation is largely based on the relative incidence and malignancy of various differential diagnoses (see pie chart). Main approaches are:
- Direct pattern recognition
- Systematic
Pattern recognition
-
Melanocytic nevus
-
Melanoma
-
Blue nevus
-
Seborrheic keratosis
_(2797064219).jpg){kind=link}
Systematic
By their relative incidences, one practical approach is:
- Is it a dysplastic (melanocytic) nevus or melanoma? See Differentiating dysplastic nevus from melanoma
If not: - Compare to patterns of various other possibilities.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel. Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision. KVAST (Swedish Society of Pathology). Retrieved on 2019-09-09.
- ↑ Page 678 in: Chhabra, Seema; Minz, RanjanaWalker; Saikia, Biman (2012). "Immunofluorescence in dermatology ". Indian Journal of Dermatology, Venereology, and Leprology 78 (6): 677. doi:. ISSN 0378-6323. Archived from the original. .
Image sources