Evaluation of suspected malignancies: Difference between revisions
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→Overall diagnosis: Expanded |
→Radicality: IHC |
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[[File:Histopathology of radically excised basal-cell carcinoma with separation artifact.jpg|thumb|250px|If tumor is seen at edge of the sample, but it is not inked, consider confirming the finding with adjacent microtomy levels, especially if no ink is seen on an inked surgical margin. In this case, a separation artifact in top image has removed a surgical margin of connective tissue, seen on adjacent microtomy section in bottom image.]] | [[File:Histopathology of radically excised basal-cell carcinoma with separation artifact.jpg|thumb|250px|If tumor is seen at edge of the sample, but it is not inked, consider confirming the finding with adjacent microtomy levels, especially if no ink is seen on an inked surgical margin. In this case, a separation artifact in top image has removed a surgical margin of connective tissue, seen on adjacent microtomy section in bottom image.]] | ||
Determine if malignant cells are located close to, or even in, any surgical resection margins. | Determine if malignant cells are located close to, or even in, any surgical resection margins. | ||
==Lymphovascular invasion== | |||
Lymphovascular invasion should always be mentioned. When present at margins, it does ''not'' count as tumor extension. | |||
<gallery mode=packed> | <gallery mode=packed> | ||
File:Histopathology of endometrial cancer with lymphovascular invasion.jpg| | File:Histopathology of endometrial cancer with lymphovascular invasion.jpg|Endometrial cancer with lymphovascular invasion. | ||
File:Histopathology of typical micropapillary urothelial carcinoma infiltrating the lamina propria - crop.jpg|If unsure whether a case is true lymphovascular invasion or a retraction artifact (imaged), use immunohistochemistry for D2-40. | |||
</gallery> | </gallery> | ||