Suspected malignant skin excisions: Difference between revisions
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*[[Melanoma]] | *[[Melanoma]] | ||
*[[Basal-cell carcinoma]] | *[[Basal-cell carcinoma]] | ||
*[[Squamous-cell | *[[Squamous-cell carcinoma of the skin]] | ||
==Gross evaluation== | ==Gross evaluation== | ||
Note: | Note: | ||
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{|class="wikitable" | {|class="wikitable" | ||
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! Condition<ref name="PaolinoDonati2017">Initially copied from: {{cite journal|last1=Paolino|first1=Giovanni|last2=Donati|first2=Michele|last3=Didona|first3=Dario|last4=Mercuri|first4=Santo|last5=Cantisani|first5=Carmen|title=Histology of Non-Melanoma Skin Cancers: An Update|journal=Biomedicines|volume=5|issue=4|year=2017|pages=71|issn=2227-9059|doi=10.3390/biomedicines5040071}} | ! Condition<ref name="PaolinoDonati2017">Initially copied from: {{cite journal|last1=Paolino|first1=Giovanni|last2=Donati|first2=Michele|last3=Didona|first3=Dario|last4=Mercuri|first4=Santo|last5=Cantisani|first5=Carmen|title=Histology of Non-Melanoma Skin Cancers: An Update|journal=Biomedicines|volume=5|issue=4|year=2017|pages=71|issn=2227-9059|doi=10.3390/biomedicines5040071}} - "This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)."</ref> !! Characteristics<ref name="PaolinoDonati2017"/> !! | ||
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| [[Actinic keratosis]] || Atypical keratinocytes confined on basal layer. | | [[Actinic keratosis]] || Atypical keratinocytes confined on basal layer. | ||
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| Keratoacanthoma || Symmetrical and circumscribed proliferation of keratinocytes, with central horn plug, with epidermis that extends over the tumor. Highly differentiated SCC. | | Keratoacanthoma || Symmetrical and circumscribed proliferation of keratinocytes, with central horn plug, with epidermis that extends over the tumor. Highly differentiated SCC. | ||
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| Invasive [[squamous cell carcinoma of the skin]] || Atypical and pleomorphic keratinocytes, involving the dermis and the sub-cutis with a potential metastatic spread. | | Invasive [[squamous-cell carcinoma of the skin]] || Atypical and pleomorphic keratinocytes, involving the dermis and the sub-cutis with a potential metastatic spread. | ||
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| Queyrat’s erytroplasia || As Bowen, but in the mucosa. | | Queyrat’s erytroplasia || As Bowen, but in the mucosa. | ||
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| Verrucous squamous cell carcinoma<ref group="notes>When present in ano-genital region, verrucous squamous cell carcinoma is also known with the term of Buschke–Löwenstein tumor</ref> || Exophytic squamous proliferation with marked papillomatosis and low atypia and the presence of koilocyte-like changes | | Verrucous squamous cell carcinoma<ref group="notes>When present in ano-genital region, verrucous squamous cell carcinoma is also known with the term of Buschke–Löwenstein tumor</ref> || Exophytic squamous proliferation with marked papillomatosis and low atypia and the presence of koilocyte-like changes | ||
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| Epithelioma cuniculatum || Squamous cell | | Epithelioma cuniculatum || Squamous-cell carcinoma of the foot. Histologically is characterized hyperkeratosis, acanthosis with an undulating, densely keratinized, well differentiated squamous epithelium, deeply penetrating the soft tissues. | ||
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| Inverted follicular keratosis || Sharply circumscribed endophytic verrucous proliferation with prominent squamous features. | | Inverted follicular keratosis || Sharply circumscribed endophytic verrucous proliferation with prominent squamous features. | ||