Immunohistochemistry: Difference between revisions
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The main methods for evaluating immunohistochemistry results are: | The main methods for evaluating immunohistochemistry results are: | ||
*Looking up each differential diagnosis at for example '''[https://www.pathologyoutlines.com/ Pathology Outlines]''' and comparing their expected staining to see which entity is most likely. | *Looking up each differential diagnosis at for example '''[https://www.pathologyoutlines.com/ Pathology Outlines]''' and comparing their expected staining to see which entity is most likely. | ||
*Paying for a subscription to '''ImmunoQuery''' | *Paying for a subscription to '''ImmunoQuery''',{{ImmunoQuery COI declaration}} where you can enter immunohistochemistry results and generate a list of most likely conditions with that profile. | ||
Preferably, immunohistochemistry results will be very specific or sensitive for a suspected condition, thereby confirming it if positive, or excluding it if negative, respectively. Even when that is not the case, immunohistochemistry can at least '''alter the likelihoods''' of different differential diagnoses. In practice, clinicians or pathologists do not state exact or even approximate numbers of likelihoods of differential diagnoses ({{further|Reporting}}<includeonly>see the [[Reporting]] chapter for phrasing uncertainty</includeonly>), since reality is too complex for that, but to demonstrate the general principle of how immunohistochemistry results can be calculated, the following formula can be used: | Preferably, immunohistochemistry results will be very specific or sensitive for a suspected condition, thereby confirming it if positive, or excluding it if negative, respectively. Even when that is not the case, immunohistochemistry can at least '''alter the likelihoods''' of different differential diagnoses. In practice, clinicians or pathologists do not state exact or even approximate numbers of likelihoods of differential diagnoses ({{further|Reporting}}<includeonly>see the [[Reporting]] chapter for phrasing uncertainty</includeonly>), since reality is too complex for that, but to demonstrate the general principle of how immunohistochemistry results can be calculated, the following formula can be used: | ||