Hepatocellular carcinoma: Difference between revisions
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→Microscopic evaluation: +Steatotic |
→Microscopic evaluation: +Triads |
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*'''Nuclei''' with increased N/C ratio, round nuclei with coarse chromatin and thickened nuclear membrane, and may have prominent nucleoli. | *'''Nuclei''' with increased N/C ratio, round nuclei with coarse chromatin and thickened nuclear membrane, and may have prominent nucleoli. | ||
*'''Steatotic''' hepatocellular carcinoma is a common variant, found most commonly in small, well-differentiated tumors.<ref name="ChanYu2016">{{cite journal|last1=Chan|first1=Anthony W H|last2=Yu|first2=Shuangni|last3=Yu|first3=Yau-Hei|last4=Tong|first4=Joanna H M|last5=Wang|first5=Lei|last6=Tin|first6=Edith K Y|last7=Chong|first7=Charing C N|last8=Chan|first8=Stephen L|last9=Wong|first9=Grace L H|last10=Wong|first10=Vincent W S|last11=Chan|first11=Henry L Y|last12=Lai|first12=Paul B S|last13=To|first13=Ka-Fai|title=Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse|journal=Histopathology|volume=69|issue=6|year=2016|pages=971–984|issn=03090167|doi=10.1111/his.13029}}</ref> | *'''Steatotic''' hepatocellular carcinoma is a common variant, found most commonly in small, well-differentiated tumors.<ref name="ChanYu2016">{{cite journal|last1=Chan|first1=Anthony W H|last2=Yu|first2=Shuangni|last3=Yu|first3=Yau-Hei|last4=Tong|first4=Joanna H M|last5=Wang|first5=Lei|last6=Tin|first6=Edith K Y|last7=Chong|first7=Charing C N|last8=Chan|first8=Stephen L|last9=Wong|first9=Grace L H|last10=Wong|first10=Vincent W S|last11=Chan|first11=Henry L Y|last12=Lai|first12=Paul B S|last13=To|first13=Ka-Fai|title=Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse|journal=Histopathology|volume=69|issue=6|year=2016|pages=971–984|issn=03090167|doi=10.1111/his.13029}}</ref> | ||
*'''Portal triads''' commonly persist in well-differentiated hepatocellular carcinomas.<ref name="MotohashiOkudaira1992">{{cite journal|last1=Motohashi|first1=Ikuko|last2=Okudaira|first2=Masahiko|last3=Takai|first3=Tomoko|last4=Kaneko|first4=Satoshi|last5=Ikeda|first5=Noriaki|title=Morphological differences between hepatocellular carcinoma and hepatocellular carcinomalike lesions|journal=Hepatology|volume=16|issue=1|year=1992|pages=118–126|issn=02709139|doi=10.1002/hep.1840160120}}</ref> | |||
<gallery mode=packed heights=200> | <gallery mode=packed heights=200> | ||