Bone marrow: Difference between revisions
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| '''Bone marrow''' from rib (or other location if applicable): Trilineage hematopoiesis. There is no evidence of malignancy. | | '''Bone marrow''' from rib (or other location if applicable): Trilineage hematopoiesis. There is no evidence of malignancy. | ||
|} | |} | ||
==Bone marrow biopsy== | |||
Evaluate the following: | |||
*'''Adequacy''': There should preferably be 5 intertrabecular spaces. | |||
*'''Cellularity''': The percentage should be 100 minus age, such as 40% in a 60 year old patient. | |||
*'''Thrombopoiesis''': There are normally about 3 megakaryocytes per 40x field. | |||
*'''Myeloid/erythroid ratio''', normally 3-4 myeloid cells per erythroid cell. | |||
*Look for any '''granuloma''' or '''cancer metastasis''' | |||
{{Bottom}} | {{Bottom}} | ||
Revision as of 14:29, 3 November 2021
Author:
Mikael Häggström [note 1]
- Myelomonocytic cells: an eosinophil myelocyte marked
- Erythroid cells: an orthochromatic erythroblast marked
- Megakaryocytic cells.
Autopsy
Microscopic evaluation
- Confirm trilineage hematopoiesis (see image).
- Look for apparent cellular atypia or decrease of cellular diversity.
Report
Example in a normal case:
| Bone marrow from rib (or other location if applicable): Trilineage hematopoiesis. There is no evidence of malignancy. |
Bone marrow biopsy
Evaluate the following:
- Adequacy: There should preferably be 5 intertrabecular spaces.
- Cellularity: The percentage should be 100 minus age, such as 40% in a 60 year old patient.
- Thrombopoiesis: There are normally about 3 megakaryocytes per 40x field.
- Myeloid/erythroid ratio, normally 3-4 myeloid cells per erythroid cell.
- Look for any granuloma or cancer metastasis
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
Image sources