Evaluation of suspected malignancies: Difference between revisions

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Mikael Häggström (talk | contribs)
Overall diagnosis: No signs of neoplasia
Mikael Häggström (talk | contribs)
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Further pinpointing of a specific tumor type is often attained by thinking of one or more possible diagnoses, and looking up their '''differential diagnoses''', followed by comparing their microscopic descriptions and multiple micrographs with the case at hand. When two or more diagnoses seem to fit with the case at hand, consider performing '''immunohistochemistry'''. Find relevant target proteins that are expected to stain substantially differently between the possible diagnoses. If it's not evident from initial sources, you may use Immunoquery.com which will generally suggest the most relevant target proteins to distinguish the suspected conditions at hand.
Further pinpointing of a specific tumor type is often attained by thinking of one or more possible diagnoses, and looking up their '''differential diagnoses''', followed by comparing their microscopic descriptions and multiple micrographs with the case at hand. When two or more diagnoses seem to fit with the case at hand, consider performing '''immunohistochemistry'''. Find relevant target proteins that are expected to stain substantially differently between the possible diagnoses. If it's not evident from initial sources, you may use Immunoquery.com which will generally suggest the most relevant target proteins to distinguish the suspected conditions at hand.


If a first glance shows '''no signs of neoplasia''' for what clinically appeared like a tumor, seek a diagnosis that can be consistent with such a clinical finding. For example, for a breast biopsy of what appeared to look like a mass, and there is no neoplasia, look mainly for dense fibrosis, so that you can report that thereby explain the finding, rather than merely write "benign breast tissue".
If a '''neoplasm has been ruled out''' for what clinically appeared like a tumor, seek a diagnosis that can be consistent with such a clinical finding. For example, for a breast biopsy of what appeared to look like a mass, and there is no neoplasia, look mainly for dense fibrosis, so that you can report that thereby explain the finding, rather than merely write "benign breast tissue".


==Staging==
==Staging==