Peritoneal fluid: Difference between revisions
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File:Pap stain of adenocarcinoma in peritoneal fluid. | File:Pap stain of adenocarcinoma in peritoneal fluid.png|Adenocarcinoma in peritoneal fluid with typical features, Pap stain. Vacuoles may be seen in both serous and mucinous adenocarcinomas. | ||
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When finding adenocarcinoma in pleural fluid in a female, and there is no other specimen, preferably perform immunostaining including PAX-8 and WT-1 to confirm a Müllerian tract origin. Also consider p53 to distinguish low-grade (wild-type staining) from high grade (aberrant staining) serous ovarian carcinoma. | When finding adenocarcinoma in pleural fluid in a female, and there is no other specimen, preferably perform immunostaining including PAX-8 and WT-1 to confirm a Müllerian tract origin. Also consider p53 to distinguish low-grade (wild-type staining) from high grade (aberrant staining) serous ovarian carcinoma. | ||
===Reporting=== | |||
Example report: | |||
{|class=wikitable | |||
| Peritoneal fluid: | |||
*Positive for malignant cells. | |||
*Adenocarcinoma. | |||
Comment: Immunohistochemistry was performed, and showed tumor cells positive for PAX-8 and WT-1, and negative (null phenotype) for p53. These findings are consistent with a tumor of Müllerian (serous) origin. | |||
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Revision as of 15:32, 14 September 2022
Author:
Mikael Häggström, M.D. [note 1]
Evaluation
Look mainly for malignancy:
-
Adenocarcinoma in peritoneal fluid with typical features, Pap stain. Vacuoles may be seen in both serous and mucinous adenocarcinomas.
When finding adenocarcinoma in pleural fluid in a female, and there is no other specimen, preferably perform immunostaining including PAX-8 and WT-1 to confirm a Müllerian tract origin. Also consider p53 to distinguish low-grade (wild-type staining) from high grade (aberrant staining) serous ovarian carcinoma.
Reporting
Example report:
Peritoneal fluid:
Comment: Immunohistochemistry was performed, and showed tumor cells positive for PAX-8 and WT-1, and negative (null phenotype) for p53. These findings are consistent with a tumor of Müllerian (serous) origin. |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
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