Evaluation of suspected malignancies: Difference between revisions

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If a suspected malignancy is present, generally check the patient '''history''' for any history of cancer, especially for tumors in more common metastasis sites, which mainly include lung, bone, liver and/or brain. If there is no known history of cancer, still consider a metastasis of unknown primary origin, especially for suspected malignancies in lymph nodes, liver, lungs, bones, or skin.<ref>Lymph nodes, liver, lungs, bones, or skin are the main sites of cancer of unknown primary origin (CUP):<br>{{cite web|url=https://www.mskcc.org/cancer-care/types/cancer-unknown-primary-origin|title=Cancer of Unknown Primary Origin|website=Memorial Sloan Kettering Cancer Center|accessdate=20222-10-14</ref>  
If a suspected malignancy is present, generally check the patient '''history''' for any history of cancer, especially for tumors in more common metastasis sites, which mainly include lung, bone, liver and/or brain. If there is no known history of cancer, still consider a metastasis of unknown primary origin, especially for suspected malignancies in lymph nodes, liver, lungs, bones, or skin.<ref>Lymph nodes, liver, lungs, bones, or skin are the main sites of cancer of unknown primary origin (CUP):<br>{{cite web|url=https://www.mskcc.org/cancer-care/types/cancer-unknown-primary-origin|title=Cancer of Unknown Primary Origin|website=Memorial Sloan Kettering Cancer Center|accessdate=20222-10-14</ref>  
{|class=wikitable align=center
{|class=wikitable align=center
| '''Histopathologic type'''<br>- see section below for descriptions<ref name="pmid25392080">{{cite journal| author=Collado Martín R, García Palomo A, de la Cruz Merino L, Borrega García P, Barón Duarte FJ, Spanish Society for Medical Oncology| title=Clinical guideline SEOM: cancer of unknown primary site. | journal=Clin Transl Oncol | year= 2014 | volume= 16 | issue= 12 | pages= 1091-7 | pmid=25392080 | doi=10.1007/s12094-014-1244-0 | pmc=4239766 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25392080  }} </ref> || '''Relative incidence''' among metastases of unknown primary origin<ref name="pmid25392080"/>
|+Metastases of unknown primary origin<ref name="pmid25392080">{{cite journal| author=Collado Martín R, García Palomo A, de la Cruz Merino L, Borrega García P, Barón Duarte FJ, Spanish Society for Medical Oncology| title=Clinical guideline SEOM: cancer of unknown primary site. | journal=Clin Transl Oncol | year= 2014 | volume= 16 | issue= 12 | pages= 1091-7 | pmid=25392080 | doi=10.1007/s12094-014-1244-0 | pmc=4239766 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25392080  }} </ref>
|-
| '''Histopathologic type'''<br>- see section below for descriptions<ref name="pmid25392080"/> || '''Relative incidence''' among metastases of unknown primary origin<ref name="pmid25392080"/>
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| Well and poorly differentiated adenocarcinomas || 50%
| Well and poorly differentiated adenocarcinomas || 50%
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