Immunofluorescense of skin tissues: Difference between revisions

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Suspicion of one or several '''immunologic diseases''':<ref name="ChhabraMinz2012">Page 678 in: {{cite journal|last1=Chhabra|first1=Seema|last2=Minz|first2=RanjanaWalker|last3=Saikia|first3=Biman|title=Immunofluorescence in dermatology|journal=Indian Journal of Dermatology, Venereology, and Leprology|volume=78|issue=6|year=2012|pages=677|issn=0378-6323|doi=10.4103/0378-6323.102355|url=https://pdfs.semanticscholar.org/23d0/148dbe342a93e0bc65a6a2e31040a89113ba.pdf}}</ref>  
Suspicion of one or several '''immunologic diseases''':<ref name="ChhabraMinz2012">Page 678 in: {{cite journal|last1=Chhabra|first1=Seema|last2=Minz|first2=RanjanaWalker|last3=Saikia|first3=Biman|title=Immunofluorescence in dermatology|journal=Indian Journal of Dermatology, Venereology, and Leprology|volume=78|issue=6|year=2012|pages=677|issn=0378-6323|doi=10.4103/0378-6323.102355|url=https://pdfs.semanticscholar.org/23d0/148dbe342a93e0bc65a6a2e31040a89113ba.pdf}}</ref>  


Suspected conditions where the direct immunofluorescence (DIF) is diagnostic:<ref name="ChhabraMinz2012"/>
Suspected conditions where the '''direct immunofluorescence (DIF) is diagnostic''':<ref name="ChhabraMinz2012"/>
*Bullous diseases
*Bullous diseases
:*Pemphigus (all forms)
:*Pemphigus (all forms)
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:*Systemic lupus erythematosus
:*Systemic lupus erythematosus


Suspected conditions where DIF is highly characteristic and of some value:<ref name="ChhabraMinz2012"/>
===Highly characteristic===
Suspected conditions where '''DIF is highly characteristic''' and of some value:<ref name="ChhabraMinz2012"/>
*Vascular diseases
*Vascular diseases
:*Allergic vasculitis
:*Allergic vasculitis
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*Lichen planus
*Lichen planus


Conditions where DIF is not diagnostic but only suggestive of immunologic pathogenesis:<ref name="ChhabraMinz2012"/>
Conditions where '''DIF is not diagnostic but only suggestive''' of immunologic pathogenesis:<ref name="ChhabraMinz2012"/>
*Connective tissue diseases
*Connective tissue diseases
:*Mixed connective tissue diseases
:*Mixed connective tissue diseases
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:*Psoriasis
:*Psoriasis


Suspected conditions where indirect immunofluorescence is generally indicated:<ref name="ChhabraMinz2012"/>
Suspected conditions where '''indirect immunofluorescence is generally indicated''':<ref name="ChhabraMinz2012"/>
*Pemphigus vulgaris
*Pemphigus vulgaris
*Pemphigus foliaceus
*Pemphigus foliaceus