Evaluation of suspected malignancies: Difference between revisions
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m →Gland-like tumors: Size |
→Gland-like tumors: Metastatic |
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:*[[Pancreatic ductal adenocarcinoma]] | :*[[Pancreatic ductal adenocarcinoma]] | ||
[[File:Well-, moderately and poorly differentiated colorectal adenocarcinoma.png|thumb|300px|Degree of differentiation, with example from a [[colorectal adenocarcinoma]].]] | [[File:Well-, moderately and poorly differentiated colorectal adenocarcinoma.png|thumb|300px|Degree of differentiation, with example from a [[colorectal adenocarcinoma]].]] | ||
Generally, adenocarcinomas are categorized by degree of differentiation as follows: | Generally, adenocarcinomas are categorized by degree of '''differentiation''' as follows: | ||
*Well differentiated: > 95% of tumor has glandular formations | *Well differentiated: > 95% of tumor has glandular formations | ||
*Moderately differentiated: 50 - 95% glandular | *Moderately differentiated: 50 - 95% glandular | ||
*Poorly differentiated: < 50% glandular | *Poorly differentiated: < 50% glandular | ||
If [[Metastasis|metastatic]] adenocarcinoma seems to be the case (always consider this in at least [[lung adenocarcinoma]]), look at the history and radiology reports for a most likely primary. Generally, perform [[immunohistochemistry]] with one or two stains that are most typical for the suspected primary, and optionally add CK7 and CK20 as a broad screening. {{further|Metastasis}} | |||
===Squamoid tumors=== | ===Squamoid tumors=== | ||