Skin: Difference between revisions
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[[File:Dark skin focalities.jpg|thumb|center|Dark skin focalities (in this case, from top left and clockwise: Spitz nevus, seborrheic keratosis, elevated melanocytic nevus and melanoma)]] | [[File:Dark skin focalities.jpg|thumb|center|Dark skin focalities (in this case, from top left and clockwise: Spitz nevus, seborrheic keratosis, elevated melanocytic nevus and melanoma)]] | ||
Skin with one or more areas that are darker than the surroundings. | Skin with one or more areas that are darker than the surroundings. | ||
[[File:Pie chart of incidence and malignancy of pigmented skin lesions.png|thumb| | [[File:Pie chart of incidence and malignancy of pigmented skin lesions.png|thumb|370px|Various diagnoses of pigmented skin lesions, by relative incidence upon biopsy, and malignancy potential.]] | ||
====Evaluation==== | ====Evaluation==== | ||
Revision as of 10:39, 17 September 2019
Author:
Mikael Häggström [note 1]
Fixation
- Generally: Buffered 4% formaldehyde.[1]
- Suspected immunologic disease:[2] Fixation for immunofluorescence, with for example Michel's solution.[1] For details, see immunofluorescense of skin tissues
See also: General notes on fixation
Presentations
Dark skin focalities
Skin with one or more areas that are darker than the surroundings.
Evaluation
By their relative incidences, a practical approach is:
- Is it a low-grade melanocytic nevus? If not:
- Is it a high-grade melanocytic nevus or melanoma? If not:
- Compare to patterns of various other possibilities.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Katarzyna Lundmark, Krynitz, Ismini Vassilaki, Lena Mölne, Annika Ternesten Bratel. Handläggning av hudprover – provtagningsanvisningar, utskärningsprinciper och snittning (Handling of skin samples - Instructions for sampling, cutting and incision. KVAST (Swedish Society of Pathology). Retrieved on 2019-09-09.
- ↑ Page 678 in: Chhabra, Seema; Minz, RanjanaWalker; Saikia, Biman (2012). "Immunofluorescence in dermatology ". Indian Journal of Dermatology, Venereology, and Leprology 78 (6): 677. doi:. ISSN 0378-6323. Archived from the original. .
Image sources