Peripheral nerve sheath tumor

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Author: Mikael Häggström [note 1]

Fixation

Generally 10% neutral buffered formalin.

Microscopic examination

Look mainly for:

  • Schwannoma, characterized by cellular Antoni A areas (top) and a loose paucicellular Antoni B areas (bottom).
    Schwannoma, characterized by cellular Antoni A areas (top) and a loose paucicellular Antoni B areas (bottom).
  • Schwannoma is also characterized by Verocay bodies (one encircled)
    Schwannoma is also characterized by Verocay bodies (one encircled)
  • Neurofibroma: A spindle cell lesion composed of slender fibroblast-like cells with storiform pattern and very low amount of stroma.
    Neurofibroma: A spindle cell lesion composed of slender fibroblast-like cells with storiform pattern and very low amount of stroma.

Notes

  1. ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

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References


Image sources


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