Lacunar infarct
Author:
Mikael Häggström [note 1]
Microscopic evaluation
On microscopy from a brain autopsy, routinely look for lacunar infarcts, especially in basal ganglia, as they are most common in the deep nuclei of the brain.[1]
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A lacunar infarct in the thalamus. -
Multiple lacunar infarcts, explained by arteriosclerosis (a severely narrowed and calcified artery seen) in basal ganglia. Lacunar infarcts may look diffusely distributed but are generally less sharply demarcated than tearing artifacts.
Differential diagnosis
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Perivascular edema, often shows a gap surrounded by disrupted (almost chicken wire-like) neuropil, but will have a more or less central blood vessel. Sometimes they also contain some inflammatory cells including siderophages (brown-golden cell in middle).
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Neuropsychology : a review of science and practice, volume III . Koffler, Sandra,, Mahone, E. (E. Mark),, Marcopulos, Bernice A.,, Johnson-Greene, Douglas Eric, 1962-, Smith, Glenn E.. New York, NY. 2018-12-17. ISBN 978-0-19-065256-2. OCLC 1078637067.
Image sources