Barrett's esophagus
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Author:
Mikael Häggström [note 1]
Contents
Microscopic examination
Generally, the main finding to look for in biopsies from the esophagus is intestinalized mucosa (Barret's esophagus), which is defined as the presence of columnar epithelium with goblet cells.[1] A true goblet cell should have rounded shape, clear to bluish cytoplasmic mucin, and be randomly scattered.[2] The mucin usually indents the nucleus.[2]
Further workup of intestinalized mucosa
If intestinalized mucosa (Barret's esophagus) is present, look for dysplasia:
Adenocarcinoma Further information: Esophageal adenocarcinoma
Also perform a screening for esophagitis. Further information: Gastroesophageal junction
Microscopy report
Incomplete Barret's esophagus does not need specific mention:
(GE junction, biopsy:) Gastroesophageal mucosa with chronic inflammation and intestinal metaplasia, consistent with Barrett's esophagus. Negative for dysplasia. |
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ . Barrett Esophagus. Stanford University School of Medicine. Retrieved on 2020-09-01.
- ↑ 2.0 2.1 Dipti M. Karamchandani. Esophagus - Premalignant - Barrett esophagus. Topic Completed: 19 March 2020, Minor changes: 29 June 2020
Image sources