View source for Benign non-inflammatory skin conditions

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|author1=[[User:Mikael Häggström|Mikael Häggström]]
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These are aberrations that do not display signs of [[Suspected malignant skin excisions|suspected malignant excisions]] or [[dermatitis]]. These may present as '''[[skin cysts]]'''.

{{Fixation - standard}}
{{Fixation - general notes}}
{{Gross processing of skin lesions with benign appearance}}
==Microscopic evaluation==
The primary objective is to determine the location, and then the most likely cell type of the aberration:

===Epidermis===
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File:Histopathology of chondrodermatitis nodularis chronica helicis.jpg|'''Ulceration''': On the outer ear, consider chondrodermatitis nodularis chronica helicis (pictured): With the ulceration surrounded by acanthosis and parakeratosis.
File:Micrograph of perinuclear vacuolization, annotated.jpg|'''Perinuclear vacuolization''', most likely insignificant as an isolated finding. In case of dermatitis, consider '''[[Vacuolar interface dermatitis]]'''
File:Prominent hyperkeratosis.jpg|'''[[Hyperkeratosis]]''', a thickening of stratum corneum
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===Dermis===
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File:Micrograph of solar elastosis.jpg|'''[[Elastosis]]''' is the buildup of elastin in tissues (actinic or "solar" elastosis pictured).
File:Histopathology of sebaceous hyperplasia.jpg|'''Sebaceous hyperplasia''': Increased volume of multiple, mature sebaceous lobules attached central dilated ducts in the upper dermis.<ref>{{cite journal|last1=Sato|first1=Toshitsugu|last2=Tanaka|first2=Masaru|title=Linear sebaceous hyperplasia on the chest|journal=Dermatology Practical & Conceptual|year=2014|issn=21609381|doi=10.5826/dpc.0401a16}}</ref>
File:Histopathology of edematous granulation tissue, low magnification.jpg|Edematous '''granulation tissue''', low magnification
File:Histopathology of edematous granulation tissue, high magnification.jpg|Edematous '''granulation tissue''', high magnification, with connective tissue, inflammatory cells and blood vessels.
File:Histopathology of desmoplasia.jpg|'''[[Desmoplasia of the skin]]''', an increase of fibrous or connective tissue
File:Histopathology of a keloid.jpg|'''[[Keloid]]''': Wide bands of collagen with large, brightly eosinophilic, glassy fibers, parallel to fibroblasts and myofibroblasts.
File:Histopathology of a hypertrophic scar, medium magnification.jpg|'''[[Hypertrophic scar]]''': Replacement of the papillary and reticular dermis by scar tissue with prominent vertically oriented blood vessels.<ref name="RabelloSouza2014">{{cite journal|last1=Rabello|first1=FB|last2=Souza|first2=CD|last3=Farina Jr|first3=JA|title=Update on hypertrophic scar treatment|journal=Clinics|volume=69|issue=8|year=2014|pages=565–573|issn=18075932|doi=10.6061/clinics/2014(08)11}}</ref>
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====Fatty tissue====
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File:Histopathology of lipoma.jpg|'''[[Lipomatous tumor]]s''' cause expansion of fatty tissue.
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