Difference between revisions of "Bone"

From patholines.org
Jump to navigation Jump to search
(Started)
 
(→‎Presentations: Correlate)
Tags: Mobile web edit, Mobile edit
 
(7 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Top
+
<noinclude>{{Top
 
|author1=[[User:Mikael Häggström|Mikael Häggström]]
 
|author1=[[User:Mikael Häggström|Mikael Häggström]]
 
|author2=
 
|author2=
Line 5: Line 5:
 
==Subregions==
 
==Subregions==
 
*[[Bone marrow]]
 
*[[Bone marrow]]
 +
 +
==Presentations==
 +
*[[Osteomyelitis]]
 +
*[[Toe]]
 +
*[[Avascular necrosis]]
 +
*'''Bone tumors''': Generally correlate with age, location and radiology.
 +
</noinclude>
 +
 +
==Grossing==
 +
To submit slides for microscopy, generally gross as follows:
 +
*'''Split''' the bone in the plane of interest for microscopy slides.
 +
*'''Fix''' the bone in formalin.
 +
*Perform '''decalcification''' of the specimen
 +
*Take the '''sections''' of interest.
  
 
==Microscopic evaluation==
 
==Microscopic evaluation==
 
Look for any of the following:
 
Look for any of the following:
 
<gallery>
 
<gallery>
File:Histopathology of acute osteomyelitis.jpg|Acute '''osteomyelitis''': Numerous neutrophils in the stroma.
+
File:Histopathology of acute osteomyelitis.jpg|Acute '''[[osteomyelitis]]''': Numerous neutrophils in the stroma.
 
</gallery>
 
</gallery>
 +
===Metastasis===
 +
Highly suspicious [[prostate adenocarcinoma]] metastasis can be confirmed with NKX1, TTF1 and CDX2.
 
{{Bottom}}
 
{{Bottom}}

Latest revision as of 14:25, 24 July 2022

Author: Mikael Häggström [note 1]

Contents

Subregions

Presentations


Grossing

To submit slides for microscopy, generally gross as follows:

  • Split the bone in the plane of interest for microscopy slides.
  • Fix the bone in formalin.
  • Perform decalcification of the specimen
  • Take the sections of interest.

Microscopic evaluation

Look for any of the following:

Metastasis

Highly suspicious prostate adenocarcinoma metastasis can be confirmed with NKX1, TTF1 and CDX2.

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References


Image sources