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Author: Mikael Häggström [note 1]




To submit slides for microscopy, generally gross as follows:

  • Split the bone in the plane of interest for microscopy slides.
  • Fix the bone in formalin.
  • Perform decalcification of the specimen. First, generally take at least a small piece to be kept separately in formalin, in case the main specimen becomes necrotic, so that you have at least one more chance to decalcify it more lightly.
  • Take the sections of interest.

Microscopic evaluation

Look for any of the following:


Highly suspicious prostate adenocarcinoma metastasis can be confirmed with NKX1, TTF1 and CDX2.


  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

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