Brain/meningeal tumor
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Author:
Mikael Häggström [note 1]
Contents
Intraoperative consultation of brain tumor fragments
Preparation
If you are expecting a brain/meningeal tumor, look at any radiology to find out what is the suspected diagnosis or differential diagnoses. A connection to the dura raises the suspicion of a meningioma. Multiple tumors raises the suspicion of metastasis or lymphoma.
Grossing
Measure the size of the specimen in 3 dimensions.
Squash prep
Remove a drop-size sample, place it on a glass-slide, then gently smear it out with another glass slide, followed by applying a fixative solution and staining with H&E.
- Evaluation
The most common primary brain tumors are:[2]
- Gliomas[3] (50.4%)
- Meningiomas[3] (20.8%)
- Pituitary adenomas[3] (15%)
- Nerve sheath tumors (10%)
Also look into the patient's history for past cancers that may have metastasized to the brain.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Image by Mikael Häggström, MD. Reference for typical findings: Chunyu Cai, M.D., Ph.D.. Meningioma. Pathology Outlines. Last author update: 10 November 2021}}
- ↑ Park, Bong Jin; Kim, Han Kyu; Sade, Burak; Lee, Joung H. (2009). "Epidemiology". Meningiomas: Diagnosis, Treatment, and Outcome . Springer. p. 11. ISBN 978-1-84882-910-7.
- ↑ 3.0 3.1 3.2 . Brain Tumors - Classifications, Symptoms, Diagnosis and Treatments (in en). www.aans.org.
Image sources