Difference between revisions of "Breast biopsy or excision"

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==Microscopic evaluation==
 
==Microscopic evaluation==
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If tumor is found, determine:
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*Tumor size
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*Tumor type, see most common conditions below.
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*Distance from excision margin
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===Most common conditions===
 
[[File:Pie chart of incidence and prognosis of histopathologic breast cancer types.png|thumb|310px|Breast cancer types, with relative incidences and prognoses.]]
 
[[File:Pie chart of incidence and prognosis of histopathologic breast cancer types.png|thumb|310px|Breast cancer types, with relative incidences and prognoses.]]
 
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File:Micrograph of a fibroadenoma.jpg|Fibroadenoma
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Revision as of 02:55, 2 October 2019

Author: Mikael Häggström [note 1]

Gross examination

Selection and trimming

  • Determine total specimen size. Optionally, determine weight[1]
  • Ink margins.Template:Ink note If sample orientations are marked, use different colors for different directions.[1]
  • Palpate specimen for masses. Compare with radiograph if available[1]
  • Make 3-4 mm thick slices.[1]
  • Submit:[1]
  • Entire specimen if it can fit in 3-5 slices.
  • If larger, 1 slice per cm of tumor (minimum of 3 slices of tumor), including both center and periphery of tumor.
  • Additional suspicious areas, including those indicated by mammography

  See also: General notes on gross processing


Report

  • Size of original tissue sample, preferably in 3 dimensions.
  • Tumor properties, at least:
  • Size in 3 dimensions.[1]
  • Distance from margins[1]
  • Consistency[1]

Microscopic evaluation

If tumor is found, determine:

  • Tumor size
  • Tumor type, see most common conditions below.
  • Distance from excision margin

Most common conditions

Breast cancer types, with relative incidences and prognoses.
Women seeking evaluation of a breast lump[2]
Finding Percentage
Fibrocystic breast changes 40%
No disease 30%
Fibroadenoma 7%
Other benign mammary dysplasias and neoplasms 13%
Breast cancer 10%

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Monika Roychowdhury. Grossing (histologic sampling) of breast lesions. Pathologyoutlines.com. Topic Completed: 1 August 2012. Revised: 19 September 2019
  2. Mitchell, Richard Sheppard; Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson (2007). Robbins Basic Pathology (8th ed.). Philadelphia: Saunders. p. 739. ISBN 978-1-4160-2973-1. 

Image sources