Difference between revisions of "Breast biopsy or excision"
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If tumor is found, determine: | If tumor is found, determine: | ||
*Tumor size | *Tumor size | ||
− | * | + | *Malignancy |
*Distance from excision margin | *Distance from excision margin | ||
− | === | + | ===Malignancy=== |
− | + | The most important is to classify a sample as either of the following: | |
+ | *Benign | ||
+ | *Carcinoma in situ | ||
+ | *Invasive cancer | ||
+ | |||
{|class="wikitable" align="center" | {|class="wikitable" align="center" | ||
|+ Women seeking evaluation of a breast lump<ref name="Kumar">{{cite book |author1=Mitchell, Richard Sheppard |author2=Kumar, Vinay |author3=Abbas, Abul K. |author4=Fausto, Nelson |title=Robbins Basic Pathology |edition=8th |publisher=Saunders |location=Philadelphia |year= 2007|page=739 |isbn=978-1-4160-2973-1 |oclc= |doi=}}</ref> | |+ Women seeking evaluation of a breast lump<ref name="Kumar">{{cite book |author1=Mitchell, Richard Sheppard |author2=Kumar, Vinay |author3=Abbas, Abul K. |author4=Fausto, Nelson |title=Robbins Basic Pathology |edition=8th |publisher=Saunders |location=Philadelphia |year= 2007|page=739 |isbn=978-1-4160-2973-1 |oclc= |doi=}}</ref> | ||
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+ | [[File:Pie chart of incidence and prognosis of histopathologic breast cancer types.png|thumb|310px|Breast cancer types, with relative incidences and prognoses.]] | ||
+ | |||
<gallery> | <gallery> | ||
File:Micrograph of a fibroadenoma.jpg|Fibroadenoma | File:Micrograph of a fibroadenoma.jpg|Fibroadenoma |
Revision as of 06:34, 2 October 2019
Author:
Mikael Häggström [note 1]
Contents
Gross examination
Selection and trimming
- Determine total specimen size. Optionally, determine weight[1]
- Ink margins.Template:Ink note If sample orientations are marked, use different colors for different directions.[1]
- Palpate specimen for masses. Compare with radiograph if available[1]
- Make 3-4 mm thick slices.[1]
- Submit:[1]
- Entire specimen if it can fit in 3-5 slices.
- If larger, 1 slice per cm of tumor (minimum of 3 slices of tumor), including both center and periphery of tumor.
- Additional suspicious areas, including those indicated by mammography
See also: General notes on gross processing
Report
- Size of original tissue sample, preferably in 3 dimensions.
- Tumor properties, at least:
Microscopic evaluation
If tumor is found, determine:
- Tumor size
- Malignancy
- Distance from excision margin
Malignancy
The most important is to classify a sample as either of the following:
- Benign
- Carcinoma in situ
- Invasive cancer
Finding | Percentage |
---|---|
Fibrocystic breast changes | 40% |
No disease | 30% |
Fibroadenoma | 7% |
Other benign mammary dysplasias and neoplasms | 13% |
Breast cancer | 10% |
- Further information: Evaluation of tumors
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Monika Roychowdhury. Grossing (histologic sampling) of breast lesions. Pathologyoutlines.com. Topic Completed: 1 August 2012. Revised: 19 September 2019
- ↑ Mitchell, Richard Sheppard; Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson (2007). Robbins Basic Pathology (8th ed.). Philadelphia: Saunders. p. 739. ISBN 978-1-4160-2973-1.
Image sources