Difference between revisions of "Breast biopsy or excision"

From patholines.org
Jump to navigation Jump to search
(Template)
Line 26: Line 26:
 
If tumor is found, determine:
 
If tumor is found, determine:
 
*Tumor size
 
*Tumor size
*Tumor type, see most common conditions below.
+
*Malignancy
 
*Distance from excision margin
 
*Distance from excision margin
  
===Most common conditions===
+
===Malignancy===
[[File:Pie chart of incidence and prognosis of histopathologic breast cancer types.png|thumb|310px|Breast cancer types, with relative incidences and prognoses.]]
+
The most important is to classify a sample as either of the following:
 +
*Benign
 +
*Carcinoma in situ
 +
*Invasive cancer
 +
 
 
{|class="wikitable" align="center"
 
{|class="wikitable" align="center"
 
|+ Women seeking evaluation of a breast lump<ref name="Kumar">{{cite book |author1=Mitchell, Richard Sheppard |author2=Kumar, Vinay |author3=Abbas, Abul K. |author4=Fausto, Nelson |title=Robbins Basic Pathology |edition=8th |publisher=Saunders |location=Philadelphia |year= 2007|page=739 |isbn=978-1-4160-2973-1 |oclc= |doi=}}</ref>
 
|+ Women seeking evaluation of a breast lump<ref name="Kumar">{{cite book |author1=Mitchell, Richard Sheppard |author2=Kumar, Vinay |author3=Abbas, Abul K. |author4=Fausto, Nelson |title=Robbins Basic Pathology |edition=8th |publisher=Saunders |location=Philadelphia |year= 2007|page=739 |isbn=978-1-4160-2973-1 |oclc= |doi=}}</ref>
Line 48: Line 52:
 
|-
 
|-
 
|}
 
|}
 +
[[File:Pie chart of incidence and prognosis of histopathologic breast cancer types.png|thumb|310px|Breast cancer types, with relative incidences and prognoses.]]
 +
 
<gallery>
 
<gallery>
 
File:Micrograph of a fibroadenoma.jpg|Fibroadenoma
 
File:Micrograph of a fibroadenoma.jpg|Fibroadenoma

Revision as of 06:34, 2 October 2019

Author: Mikael Häggström [note 1]

Gross examination

Selection and trimming

  • Determine total specimen size. Optionally, determine weight[1]
  • Ink margins.Template:Ink note If sample orientations are marked, use different colors for different directions.[1]
  • Palpate specimen for masses. Compare with radiograph if available[1]
  • Make 3-4 mm thick slices.[1]
  • Submit:[1]
  • Entire specimen if it can fit in 3-5 slices.
  • If larger, 1 slice per cm of tumor (minimum of 3 slices of tumor), including both center and periphery of tumor.
  • Additional suspicious areas, including those indicated by mammography

  See also: General notes on gross processing


Report

  • Size of original tissue sample, preferably in 3 dimensions.
  • Tumor properties, at least:
  • Size in 3 dimensions.[1]
  • Distance from margins[1]
  • Consistency[1]

Microscopic evaluation

If tumor is found, determine:

  • Tumor size
  • Malignancy
  • Distance from excision margin

Malignancy

The most important is to classify a sample as either of the following:

  • Benign
  • Carcinoma in situ
  • Invasive cancer
Women seeking evaluation of a breast lump[2]
Finding Percentage
Fibrocystic breast changes 40%
No disease 30%
Fibroadenoma 7%
Other benign mammary dysplasias and neoplasms 13%
Breast cancer 10%
Breast cancer types, with relative incidences and prognoses.
Further information: Evaluation of tumors

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Monika Roychowdhury. Grossing (histologic sampling) of breast lesions. Pathologyoutlines.com. Topic Completed: 1 August 2012. Revised: 19 September 2019
  2. Mitchell, Richard Sheppard; Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson (2007). Robbins Basic Pathology (8th ed.). Philadelphia: Saunders. p. 739. ISBN 978-1-4160-2973-1. 

Image sources