Breast biopsy or excision
Revision as of 06:34, 2 October 2019 by Mikael Häggström (talk | contribs) (→Microscopic evaluation: Introduced)
Author:
Mikael Häggström [note 1]
Contents
Gross examination
Selection and trimming
- Determine total specimen size. Optionally, determine weight[1]
- Ink margins.Template:Ink note If sample orientations are marked, use different colors for different directions.[1]
- Palpate specimen for masses. Compare with radiograph if available[1]
- Make 3-4 mm thick slices.[1]
- Submit:[1]
- Entire specimen if it can fit in 3-5 slices.
- If larger, 1 slice per cm of tumor (minimum of 3 slices of tumor), including both center and periphery of tumor.
- Additional suspicious areas, including those indicated by mammography
See also: General notes on gross processing
Report
- Size of original tissue sample, preferably in 3 dimensions.
- Tumor properties, at least:
Microscopic evaluation
If tumor is found, determine:
- Tumor size
- Malignancy
- Distance from excision margin
Malignancy
The most important is to classify a sample as either of the following:
- Benign
- Carcinoma in situ
- Invasive cancer
Finding | Percentage |
---|---|
Fibrocystic breast changes | 40% |
No disease | 30% |
Fibroadenoma | 7% |
Other benign mammary dysplasias and neoplasms | 13% |
Breast cancer | 10% |
- Further information: Evaluation of tumors
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Monika Roychowdhury. Grossing (histologic sampling) of breast lesions. Pathologyoutlines.com. Topic Completed: 1 August 2012. Revised: 19 September 2019
- ↑ Mitchell, Richard Sheppard; Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson (2007). Robbins Basic Pathology (8th ed.). Philadelphia: Saunders. p. 739. ISBN 978-1-4160-2973-1.
Image sources