Difference between revisions of "Cholecystitis"
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==Microscopic evaluation== | ==Microscopic evaluation== | ||
===Findings in '''acute''' cholecystisis=== | ===Findings in '''acute''' cholecystisis=== | ||
| − | *Initially edema, congestion, hemorrhage, fibrin deposition in and around muscular layer | + | Typical features:<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/gallbladderacutecholecystitis.html|title=Gallbladder & extrahepatic bile ducts - Cholecystitis|author=Hanni Gulwani|website=Pathology Outlines}} Topic Completed: 1 September 2012. Minor changes: 5 September 2019</ref> |
| − | *Later | + | *Initially edema, congestion, hemorrhage, fibrin deposition in and around the muscular layer. |
| − | *Variable reactive epithelial changes | + | *Later necrosis of the mucosa and and deeper layers, with neutrophils |
| − | + | *Variable reactive epithelial changes, which may resemble dysplasia | |
| − | + | There may be fresh thrombi within small veins | |
===Findings in '''chronic''' cholecystitis=== | ===Findings in '''chronic''' cholecystitis=== | ||
Revision as of 16:00, 13 August 2020
Author:
Mikael Häggström [note 1]
Inflammation of the gallbladder:
Contents
Gross processing
As per basic Gallbladder.
Microscopic evaluation
Findings in acute cholecystisis
Typical features:[1]
- Initially edema, congestion, hemorrhage, fibrin deposition in and around the muscular layer.
- Later necrosis of the mucosa and and deeper layers, with neutrophils
- Variable reactive epithelial changes, which may resemble dysplasia
There may be fresh thrombi within small veins
Findings in chronic cholecystitis
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Typical features are:[2]
- Smooth muscle hypertrophy in the muscularis
- Mild inflammatory infiltrates
- Rokitansky-Aschoff sinuses
Other findings favoring the diagnosis are:[2]
- Granulomas (from ruptured Rokitansky-Aschoff sinuses) strogly favor the diagnosis.
- Hyalinized collagen
- Dystrophic calcification
- Lymphoid aggregates
- Atrophic and/or ulcerated mucosa
- Metaplastic changes, such as gastric or intestinal mucosa
Eosinophilic cholecystitis
For a general gallbladder screening, see gallbladder.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ Hanni Gulwani. Gallbladder & extrahepatic bile ducts - Cholecystitis. Pathology Outlines. Topic Completed: 1 September 2012. Minor changes: 5 September 2019
- ↑ 2.0 2.1 Hanni Gulwani. Gallbladder - Cholecystitis - Chronic cholecystitis. Topic Completed: 1 September 2012. Revised: 9 January 2020
Image sources
